CAJ | 학술논문

目的探讨第13组淋巴结是否可作为前哨淋巴结预测壶腹周围癌淋巴结转移情况.方法选择2009年1月至2012年1月中国医学科学院肿瘤医院77例行Whipple术的壶腹周围癌.其中26例(试验组,男18例、女8例,年龄38 ～ 79岁)行Whipple术中,采用1％亚甲蓝或纳米碳混悬液术中瘤床注射,另外5l例作为对照组不注射,其中男33例、女l8例,年龄33～78岁.对染色的第13组淋巴结进行活检,之后常规行淋巴结清扫术,并对淋巴结转移情况进行研究.结果试验组患者在瘤床注射1％亚甲蓝或纳米碳混悬液能够显示出肿瘤淋巴结的引流范围；对照组和试验组患者平均清扫淋巴结个数分别为15.8(3 ～54)个和17.6(6～ 40)个,差异无统计学意义(P=0.460).结论第13组淋巴结可能并不适合作为前哨淋巴结用于预测胰腺及壶腹周围癌淋巴结转移情况.
목적 탐토제13조림파결시부가작위전초림파결예측호복주위암림파결전이정황.방법 선택2009년1월지2012년1월중국의학과학원종류의원77례행Whipple술적호복주위암.기중26례(시험조,남18례、녀8례,년령38 ～ 79세)행Whipple술중,채용1％아갑람혹납미탄혼현액술중류상주사,령외5l례작위대조조불주사,기중남33례、녀l8례,년령33～78세.대염색적제13조림파결진행활검,지후상규행림파결청소술,병대림파결전이정황진행연구.결과 시험조환자재류상주사1％아갑람혹납미탄혼현액능구현시출종류림파결적인류범위；대조조화시험조환자평균청소림파결개수분별위15.8(3 ～54)개화17.6(6～ 40)개,차이무통계학의의(P=0.460).결론 제13조림파결가능병불괄합작위전초림파결용우예측이선급호복주위암림파결전이정황.
Objective To study the feasibility and clinical value of 13th lymph nodes in predicting general lymph nodes metastases for periampullary carcinoma.Methods A total of 77 patients with pathologically confirmed periampullary carcinoma were recruited.And 26 (18 males and 8 females,age 38-79 years) of them underwent Whipple procedures during which 1％ methylene blue or nanogate carbon was injected into tumor bed.The othor 51 patients as controls (33 males,18 females,age 38-78 years).The dyed 13th lymph nodes were biopsied.Then routine lymphadenectomy was performed and their pathological results were analyzed.Results In the experimental group,the lymph node drainage area of cancer was identified.However,in contrast with 51 patients in the control group,the labeling of 13th lymph nodes did not significantly increase the number of cleaned lymph nodes (15.8 (3-54) vs 17.6 (6-40),P =0.460).Conclusion 13th lymph nodes are non-suitable as sentinels for predicting general lymph nodes metastases of periampullary carcinoma.