CAJ | 학술논문

目的比较阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者持续气道正压通气(CPAP)治疗压力的自动与人工调定.方法选择2010年12月至2012年12月在广州医学院第一附属医院睡眠呼吸中心确诊为OSAHS的患者进行人工与自动CPAP治疗压力调定,人工调压法在多导睡眠图监测下进行,自动调压法则根据患者在家连续调压3晚至1周的结果.比较两种调压方法产生的压力.结果共纳入58例患者,其中男52例、女6例,年龄(48±ll)岁.自动调定的压力为(10.0±2.2)cmH2O(1 cmH2O=0.098 kPa),显著高于人工调定的(7.5±1.5)cm H2O(P =0.000).按人工调定的压力对患者进行CPAP治疗后,睡眠呼吸暂停低通气指数从(54.0±21.0)次/h降至(3.8±2.5)次/h(P＜0.01).结论自动调定的压力常高于人工调定的压力,如患者不能耐受自动调定的压力,应重新进行人工调定.
목적 비교조새성수면호흡잠정저통기종합정(OSAHS)환자지속기도정압통기(CPAP)치료압력적자동여인공조정.방법 선택2010년12월지2012년12월재엄주의학원제일부속의원수면호흡중심학진위OSAHS적환자진행인공여자동CPAP치료압력조정,인공조압법재다도수면도감측하진행,자동조압법칙근거환자재가련속조압3만지1주적결과.비교량충조압방법산생적압력.결과 공납입58례환자,기중남52례、녀6례,년령(48±ll)세.자동조정적압력위(10.0±2.2)cmH2O(1 cmH2O=0.098 kPa),현저고우인공조정적(7.5±1.5)cm H2O(P =0.000).안인공조정적압력대환자진행CPAP치료후,수면호흡잠정저통기지수종(54.0±21.0)차/h강지(3.8±2.5)차/h(P＜0.01).결론 자동조정적압력상고우인공조정적압력,여환자불능내수자동조정적압력,응중신진행인공조정.
Objective To compare the continuous positive airway pressure (CPAP) of automatic titration with that of manual titration.Methods A total of 58 patients with obstructive sleep apnea and hypopnea syndrome (OSAHS) diagnosed by overnight polysomnography at sleep center of First Affiliated Hospital,Guangzhou Medical University were studied between December 2010 and December 2012.Manual titration was performed under full polysmnography and auto-titration at home for 3-7 nights.Results There were 52 males and 6 females with an age range of (48 ± 11) years.CPAP pressure titrated by automatic device (10.0 ±2.2) cm H2O (1 cm H2O =0.098 kPa) was significantly higher than that titrated manually (7.5 ± 1.5) cm H2O (P =0.000).Apnea-hyponea index decreased significantly from (54.0 ± 21.0) events/h pre-treatment to (3.8 ± 2.5) events/h post-treatment under manual titration (P ＜ 0.01).Conclusions CPAP pressure titrated by automatic device is usually higher than that titrated manually.Manual titration should be performed if a patient can not tolerate the CPAP pressure titrated by an automatic device.