中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2013年
37期
2969-2971
,共3页
肌疲劳%肌疾病%创伤和损伤%基因型
肌疲勞%肌疾病%創傷和損傷%基因型
기피로%기질병%창상화손상%기인형
Muscle fatigue%Musclar diseases%Wounds and injuries%Genetype
目的 探讨CNTF基因多态性与运动员肌肉组织训练适应性的关系.方法 测定某院校体育专业215名无训练史学生CNTF基因型,并于训练过程中检测试验对象肱二头肌肌腹横截面积变化,检测其肌肉疲劳及肌肉损伤相关生化指标.分析基因多态性对检测结果的影响.结果 检测对象完成新训过程后,肱二头肌横截面积均有不同程度的增长,其中GG基因型增长幅度大于其他基因型(F=8.823,P＜0.05).在新训结束时的体能考核后,各组检测对象相关指标仍高于对照组,但GG型检测对象血乳酸、血尿素氮、血清肌酸激酶值低于其他各组[(234.7 ±57.5)比(84.7±24.7)U,(5.8±0.8)比(4.3 ±0.6)mmol/L,(271.5 ±98.7)比(59.2±35.6)U](P＜0.05).结论 GG型检测肌肉横截面积增加较多,肌肉损伤相关血清指标增高较小;GG对象肌肉组织训练适应性优于GA、AA型.
目的 探討CNTF基因多態性與運動員肌肉組織訓練適應性的關繫.方法 測定某院校體育專業215名無訓練史學生CNTF基因型,併于訓練過程中檢測試驗對象肱二頭肌肌腹橫截麵積變化,檢測其肌肉疲勞及肌肉損傷相關生化指標.分析基因多態性對檢測結果的影響.結果 檢測對象完成新訓過程後,肱二頭肌橫截麵積均有不同程度的增長,其中GG基因型增長幅度大于其他基因型(F=8.823,P＜0.05).在新訓結束時的體能攷覈後,各組檢測對象相關指標仍高于對照組,但GG型檢測對象血乳痠、血尿素氮、血清肌痠激酶值低于其他各組[(234.7 ±57.5)比(84.7±24.7)U,(5.8±0.8)比(4.3 ±0.6)mmol/L,(271.5 ±98.7)比(59.2±35.6)U](P＜0.05).結論 GG型檢測肌肉橫截麵積增加較多,肌肉損傷相關血清指標增高較小;GG對象肌肉組織訓練適應性優于GA、AA型.
목적 탐토CNTF기인다태성여운동원기육조직훈련괄응성적관계.방법 측정모원교체육전업215명무훈련사학생CNTF기인형,병우훈련과정중검측시험대상굉이두기기복횡절면적변화,검측기기육피로급기육손상상관생화지표.분석기인다태성대검측결과적영향.결과 검측대상완성신훈과정후,굉이두기횡절면적균유불동정도적증장,기중GG기인형증장폭도대우기타기인형(F=8.823,P＜0.05).재신훈결속시적체능고핵후,각조검측대상상관지표잉고우대조조,단GG형검측대상혈유산、혈뇨소담、혈청기산격매치저우기타각조[(234.7 ±57.5)비(84.7±24.7)U,(5.8±0.8)비(4.3 ±0.6)mmol/L,(271.5 ±98.7)비(59.2±35.6)U](P＜0.05).결론 GG형검측기육횡절면적증가교다,기육손상상관혈청지표증고교소;GG대상기육조직훈련괄응성우우GA、AA형.
Objective To explore the relationship between CNTF gene polymorphism and athletes training adaptation of muscle tissue.Methods A total of 215 new students without a training history CNTF genotype were recruited from a sports college.During training,the changes in test object biceps muscle belly cross-sectional area,muscle fatigue and muscle damage related biochemical indices were detected.And the impact of gene polymorphism was analyzed on the detection results.Results After training,biceps brachii muscle cross-sectional areas showed different degrees of growth and the GG gene type growth was greater than other genotypes(P ＜0.05).At post-training physical examination,all subjects of muscle fatigue and muscle damage index were higher than those of the control group,but no obvious difference existed between examination groups.In basic training at the end of physical examination,the related indices of each group were higher than those of the control group,but the values of lactic acid,blood urea nitrogen and serum CK value were lower for object type GG than those for the other groups [(234.7 ± 57.5) vs (84.7 ± 24.7) U,(5.8±0.8) vs (4.3 ±0.6)mmol/L,(271.5 ±98.7) vs (59.2±35.6) U] (P ＜0.05).Conclusion During training,muscle cross-sectional area of GG genotype grows more while the serum levels of muscle injury are significantly lower than those of other groups.In summary,GG genotype has better muscle training adaptation than GA and AA.
