CAJ | 학술논문

目的探讨超声引导下聚桂醇硬化治疗子宫肌瘤的疗效.方法对102例育龄期子宫肌瘤患者的1 13个肌瘤行超声引导下聚桂醇硬化治疗,于术前及术后1、3、6、12个月行常规超声及彩色多普勒超声检查,比较治疗前后肌瘤体积及血供的变化;并以症状严重性评分调查问卷形式评估患者临床症状的变化.结果治疗后1、3、6及12个月,肌瘤体积较术前分别平均缩小40％、47％、58％及70％(P＜0.05);治疗前后患者症状严重性评分之间的差异有统计学意义(P=0.000);术中及术后无严重并发症发生.结论超声引导下聚桂醇硬化治疗子宫肌瘤是安全、有效的微创治疗子宫肌瘤的方法,值得临床推广应用.
목적 탐토초성인도하취계순경화치료자궁기류적료효.방법 대102례육령기자궁기류환자적1 13개기류행초성인도하취계순경화치료,우술전급술후1、3、6、12개월행상규초성급채색다보륵초성검사,비교치료전후기류체적급혈공적변화;병이증상엄중성평분조사문권형식평고환자림상증상적변화.결과 치료후1、3、6급12개월,기류체적교술전분별평균축소40％、47％、58％급70％(P＜0.05);치료전후환자증상엄중성평분지간적차이유통계학의의(P=0.000);술중급술후무엄중병발증발생.결론 초성인도하취계순경화치료자궁기류시안전、유효적미창치료자궁기류적방법,치득림상추엄응용.
Objective To evaluate the safety and efficacies of ultrasound-guided sclerotherapy of uterine fibroids with lauromacrogol.Methods A total of 102 consecutive premenopausal women with 113 uterine fibroids were enrolled.The treatment of lauromacrogol was performed under the guidance of ultrasound.Both conventional and color Doppler ultrasound were performed before treatment and at Month 1,3,6 and 12 after treatment.The changes of tumor volume reductions and vascular flow were analyzed and compared.And the alteration of symptoms was evaluated by the symptom severity score (SSS) questionnaire.And adverse events were also assessed during and after treatment.Results At Month 1,3,6 and 12 after treatment,the mean volume of fibroids decreased by 40％,47％,58％ and 70％ respectively.And the differences had statistical significance before and after treatment (P ＜ 0.05).The clinical symptoms alleviated greatly or even disappeared.And the differences in SSS before and after treatment were also statistically significant (P =0.000).There was no onset of severe adverse events.Conclusion Both safe and efficacious,ultrasound-guided sclerotherapy of uterine fibroids with lauromacrogolis offers an alternative option for patients with fertility requirements.