CAJ | 학술논문

目的探讨中老年人群高静息心率对颈动脉斑块稳定性的影响.方法在参加2006-2007年健康体检的开滦(集团)有限责任公司在职及离退休职工101 510人中分层随机抽取5 852人作为观察人群,于2010-2011年对观察人群进行健康体检,同时进行了颈动脉超声检查,采用Logistic回归分析颈动脉稳定和不稳定斑块的影响因素.结果最终纳入分析4 894例中老年人群(男2 945例,女1 949例),年龄40 ～ 95岁.低静息心率组颈动脉稳定、不稳定斑块检出率分别为25.7％、25.4％,高静息心率组颈动脉稳定、不稳定斑块检出率分别为23.8％、33.2％;调整其他危险因素后,高静息心率组发生不稳定斑块风险比低静息心率组增加29％,其OR值为1.290(95％ CI1.039 ～1.062).结论高静息心率能增加中老年人群颈动脉不稳定斑块的发生风险.
목적 탐토중노년인군고정식심솔대경동맥반괴은정성적영향.방법 재삼가2006-2007년건강체검적개란(집단)유한책임공사재직급리퇴휴직공101 510인중분층수궤추취5 852인작위관찰인군,우2010-2011년대관찰인군진행건강체검,동시진행료경동맥초성검사,채용Logistic회귀분석경동맥은정화불은정반괴적영향인소.결과 최종납입분석4 894례중노년인군(남2 945례,녀1 949례),년령40 ～ 95세.저정식심솔조경동맥은정、불은정반괴검출솔분별위25.7％、25.4％,고정식심솔조경동맥은정、불은정반괴검출솔분별위23.8％、33.2％;조정기타위험인소후,고정식심솔조발생불은정반괴풍험비저정식심솔조증가29％,기OR치위1.290(95％ CI1.039 ～1.062).결론 고정식심솔능증가중노년인군경동맥불은정반괴적발생풍험.
Objective To explore the effect of high resting heart rate (RHR) on the stability of carotid artery plaque in a middle and advanced aged population.Methods During 2010-2011,a total of 5 852 participants were selected randomly from 101 510 workers of a Tangshan Kailuan company.RHR was measured and carotid artery ultrasound performed to detect the carotid artery plaque.Logistic regression was performed to analyze the influencing factors of carotid artery stable and unstable plaque.Results There were 4 894 subjects aged 40-95 years,including 2 945 males and 1 949 females.The detection rates of carotid artery stable and unstable plaque were 25.7％ and 25.4％ in low RHR group versus 23.8％ and 33.2％ in high RHR group.Compared with low RHR group,the risk of carotid artery unstable plaque increased to 29％ in high RHR group after adjusting for all influencing factors.The odds ratio was 1.290 (95％ CI 1.039-1.062).Conclusion High RHR can increase the risk of carotid artery unstable plaque in middle and advanced aged population.