CAJ | 학술논문

目的通过二维和三维超声测量胎儿胸腺横径、前后径和体积,建立胎儿胸腺发育正常参考值,评估胎儿不同孕周胸腺发育和胎儿宫内生长迟缓的相关性.方法取2012年12月-2014年5月于吉林大学第二医院妇产科疑诊为胎儿宫内生长迟缓的53例孕妇作为观察组,同时随机选取53例相应孕周孕妇作为对照组,二维超声在三血管切面测量胎儿胸腺横径、前后径,三维超声多切面法测量胎儿胸腺体积,对照组参数行线性回归分析,两组参数行秩和检验,以P ＜0.05为差异有统计学意义.结果对照组胎儿胸腺横径和孕周回归方程为y=0.14X-1.174,R2=0.766,P＜0.05;对照组胎儿胸腺前后径和孕周回归方程为Y=0.49X-0.166,R2 =0.792,P＜0.05;对照组胎儿胸腺体积和孕周回归方程为Y=0.652X-10.611,R2=0.791,P＜0.05.两组参数行符号秩和检验,渐近显著性均P＜0.05.结论胎儿胸腺横径、前后径和体积随孕周增加而增大,胎儿宫内生长迟缓时胸腺横径、前后径和体积小于同孕龄胎儿胸腺.
목적 통과이유화삼유초성측량태인흉선횡경、전후경화체적,건립태인흉선발육정상삼고치,평고태인불동잉주흉선발육화태인궁내생장지완적상관성.방법 취2012년12월-2014년5월우길림대학제이의원부산과의진위태인궁내생장지완적53례잉부작위관찰조,동시수궤선취53례상응잉주잉부작위대조조,이유초성재삼혈관절면측량태인흉선횡경、전후경,삼유초성다절면법측량태인흉선체적,대조조삼수행선성회귀분석,량조삼수행질화검험,이P ＜0.05위차이유통계학의의.결과 대조조태인흉선횡경화잉주회귀방정위y=0.14X-1.174,R2=0.766,P＜0.05;대조조태인흉선전후경화잉주회귀방정위Y=0.49X-0.166,R2 =0.792,P＜0.05;대조조태인흉선체적화잉주회귀방정위Y=0.652X-10.611,R2=0.791,P＜0.05.량조삼수행부호질화검험,점근현저성균P＜0.05.결론 태인흉선횡경、전후경화체적수잉주증가이증대,태인궁내생장지완시흉선횡경、전후경화체적소우동잉령태인흉선.
Objective To measure the ultrasonic parameters of transverse diameter,anteroposterior diameter and volume of fetal thymus through two and three-dimensional (2D and 3D) probes,establish normal reference range of fetal thymus development and assess the correlation between fetal intrauterine growth restriction and fetal thymus development.Methods A total of 53 patients with suspected fetal intrauterine growth restriction (IUGR) at our hospital from December 2012 to May 2014 were selected into the observation group while another 53 cases as the control group corresponding to the former group's gestational week (GA).The transverse and anteroposterior diameters were measured in the three vessel view by 2D-ultrasound and the volume of fetal thymus was measured through 3D ultrasound.The control parameters were analyzed by linear regression analysis.And two groups of parameters were tested by rank sum test.P ＜ 0.05 was deemed significant.Results The regression equation of fetal thymus transverse diameter and GA was:Y=0.14X-1.174,R2 =0.766,P ＜0.05 ; the regression equation of fetal thymus anteroposterior diameter and GA was:Y =0.49X-0.166,R2 =0.792,P ＜ 0.05 ; the regression equation of fetal thymus volume and GA was:Y=0.652X-10.611,R2 =0.791,P ＜0.05.Two groups underwent rank sum test of fetal thymus transverse diameter,anteroposterior diameter and volume (P ＜ 0.05).Conclusion Fetal thymus transverse diameter,anteroposterior diameter and volume increase with gestational weeks.In IUGR,fetal thymus transverse diameter,anteroposterior diameter and volume are less than those of the same GA fetal thymus.