中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2014年
35期
2750-2753
,共4页
赵英华%韩新爱%胡绍勇%石星亮%赵静%孙尔维%李绍林
趙英華%韓新愛%鬍紹勇%石星亮%趙靜%孫爾維%李紹林
조영화%한신애%호소용%석성량%조정%손이유%리소림
脊柱炎,强直性%磁共振成像%骶髂关节
脊柱炎,彊直性%磁共振成像%骶髂關節
척주염,강직성%자공진성상%저가관절
Spondylitis,ankylosing%Magnetic resonance imaging%Sacroiliac joint
目的 评估扩散加权序列及对比增强MRI观察强直性脊柱炎活动组、稳定组及对照组的意义,探讨强直性脊柱炎骶髂关节ADC值、T1强化率与临床活性指标的相关性.方法 前瞻性的筛选2010年5月至2013年4月南方医科大学第三附属医院风湿免疫科56例强直性脊柱炎患者,活动组32例、稳定期24例,健康对照组20例.MR检查测量骶髂关节的表观扩散系数(ADC)值及T1强化率(△SI),炎性活动指标:Bath强直性脊柱炎病情活动指数(BASDAI评分)、血沉及C-反应蛋白,统计学分析强直性脊柱炎活动组、稳定组及对照组的各参数差异是否有统计学意义,评估ADC值、T1强化率与BASDAI评分、血沉及C-反应蛋白的相关性.结果 ADC值活动组、稳定组及健康对照组分别为(1.45±0.25)× 10-3、(0.67±0.10)×10-3及(0.32±0.11)×10-3 mm2/s,与活动组比较差异均有统计学意义(均P＜0.01).T1强化率3组差异均有统计学意义(均P＜0.01),ADC值、△SI与BASDAI评分显著相关(r=0.824,0.794;均P＜0.01).结论 扩散加权序列及对比增强序列对判断AS活动性优于临床活动性指标,结合临床活性指标可明显提高评价AS是否活动的准确性.
目的 評估擴散加權序列及對比增彊MRI觀察彊直性脊柱炎活動組、穩定組及對照組的意義,探討彊直性脊柱炎骶髂關節ADC值、T1彊化率與臨床活性指標的相關性.方法 前瞻性的篩選2010年5月至2013年4月南方醫科大學第三附屬醫院風濕免疫科56例彊直性脊柱炎患者,活動組32例、穩定期24例,健康對照組20例.MR檢查測量骶髂關節的錶觀擴散繫數(ADC)值及T1彊化率(△SI),炎性活動指標:Bath彊直性脊柱炎病情活動指數(BASDAI評分)、血沉及C-反應蛋白,統計學分析彊直性脊柱炎活動組、穩定組及對照組的各參數差異是否有統計學意義,評估ADC值、T1彊化率與BASDAI評分、血沉及C-反應蛋白的相關性.結果 ADC值活動組、穩定組及健康對照組分彆為(1.45±0.25)× 10-3、(0.67±0.10)×10-3及(0.32±0.11)×10-3 mm2/s,與活動組比較差異均有統計學意義(均P＜0.01).T1彊化率3組差異均有統計學意義(均P＜0.01),ADC值、△SI與BASDAI評分顯著相關(r=0.824,0.794;均P＜0.01).結論 擴散加權序列及對比增彊序列對判斷AS活動性優于臨床活動性指標,結閤臨床活性指標可明顯提高評價AS是否活動的準確性.
목적 평고확산가권서렬급대비증강MRI관찰강직성척주염활동조、은정조급대조조적의의,탐토강직성척주염저가관절ADC치、T1강화솔여림상활성지표적상관성.방법 전첨성적사선2010년5월지2013년4월남방의과대학제삼부속의원풍습면역과56례강직성척주염환자,활동조32례、은정기24례,건강대조조20례.MR검사측량저가관절적표관확산계수(ADC)치급T1강화솔(△SI),염성활동지표:Bath강직성척주염병정활동지수(BASDAI평분)、혈침급C-반응단백,통계학분석강직성척주염활동조、은정조급대조조적각삼수차이시부유통계학의의,평고ADC치、T1강화솔여BASDAI평분、혈침급C-반응단백적상관성.결과 ADC치활동조、은정조급건강대조조분별위(1.45±0.25)× 10-3、(0.67±0.10)×10-3급(0.32±0.11)×10-3 mm2/s,여활동조비교차이균유통계학의의(균P＜0.01).T1강화솔3조차이균유통계학의의(균P＜0.01),ADC치、△SI여BASDAI평분현저상관(r=0.824,0.794;균P＜0.01).결론 확산가권서렬급대비증강서렬대판단AS활동성우우림상활동성지표,결합림상활성지표가명현제고평개AS시부활동적준학성.
Objective To evaluate the value of judging for the activity in AS by diffusion-weighted sequences (DWI) and enhance sequences MRI(DCE-MRI),to explore the correlation of Apparent diffusion coefficient(ADC) values,intensive rate and the clinical activity index in sacroiliitis (SIJ) of ankylosing spondylitis (AS).Methods 56 patients prospectively choiced and diagnosed were divided into two groupsas,active group (n =32) and chronic group (n =24) by rheumatologist according to BASDAI and laboratory parameters.Twenty healthy adults were as control group.The values of ADC and intensive rate of all sacroiliac joints (SIJs) were measured on MRI.BASDAI score were got by Bath ankylosing spondylitis disease activity index.ESR,CPR and were got by laboratory.Statisticaly to analysis whether the parameters were significantly different amang AS active,chronic,and the control group.To assess the correlation of the values of ADC,intensive rate and BASDAI score,ESR,CPR and in SIJ.Results the values of ADC and intensive rate were significantly different among AS active,chronic and the control group.There were the significant correlation between the values of ADC,intensive rate and BASDAI score.Conclusion Diffusion-weighted sequences and Contrast-enhanced sequences is superior to other methods in judging the activity in AS.combined with clinical activity index,the accuracy can significantly be improved to explore whether the activities of AS are.
