中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2014年
37期
2945-2947
,共3页
早发型重度子痫前期%并发症%母婴结局
早髮型重度子癇前期%併髮癥%母嬰結跼
조발형중도자간전기%병발증%모영결국
Early onset severe pre-eclampsia%Complication%Maternal and neonatal outcome
目的 探讨早发型重度子痫前期的临床特征及母婴预后.方法 选取2009年1月至2011年12月在山东省滕州市妇幼保健院收治的早发型重度子痫前期孕妇,共126例.根据发病孕周分为3组,A组:孕周＜28周,36例;B组:28周≤孕周＜32周,40例;C组:32周≤孕周＜34周,50例.比较3组的临床特征及母婴结局.结果 3组孕妇入院时血压、24h尿蛋白定量、血小板参数、尿素氮、D-2聚体及血肌酐分析差异均无统计学意义(均P＞0.05);3组并发症发生率随发病孕周延长而下降,3组孕妇终止妊娠时并发症的构成差异无统计学意义(P＞0.05);新生儿窒息A、B、C组例数分别为33(100％)、18(50％)和9(19％),3组间差异有统计学意义.围产儿死亡率3组间差异均有统计学意义(均P ＜0.05);期待治疗时间,B组期明显长于其他两组,差异均有统计学意义(均P＜0.05),而A、C组差异无统计学意义(P＞0.05).各组患者的分娩方式多以剖宫产为主.结论 早发型重度子痫前期新生儿窒息和围产儿死亡率随发病孕周延长而降低,应及早诊断、积极治疗、严密监测母胎情况,适时终止妊娠,降低围产儿死亡率.
目的 探討早髮型重度子癇前期的臨床特徵及母嬰預後.方法 選取2009年1月至2011年12月在山東省滕州市婦幼保健院收治的早髮型重度子癇前期孕婦,共126例.根據髮病孕週分為3組,A組:孕週＜28週,36例;B組:28週≤孕週＜32週,40例;C組:32週≤孕週＜34週,50例.比較3組的臨床特徵及母嬰結跼.結果 3組孕婦入院時血壓、24h尿蛋白定量、血小闆參數、尿素氮、D-2聚體及血肌酐分析差異均無統計學意義(均P＞0.05);3組併髮癥髮生率隨髮病孕週延長而下降,3組孕婦終止妊娠時併髮癥的構成差異無統計學意義(P＞0.05);新生兒窒息A、B、C組例數分彆為33(100％)、18(50％)和9(19％),3組間差異有統計學意義.圍產兒死亡率3組間差異均有統計學意義(均P ＜0.05);期待治療時間,B組期明顯長于其他兩組,差異均有統計學意義(均P＜0.05),而A、C組差異無統計學意義(P＞0.05).各組患者的分娩方式多以剖宮產為主.結論 早髮型重度子癇前期新生兒窒息和圍產兒死亡率隨髮病孕週延長而降低,應及早診斷、積極治療、嚴密鑑測母胎情況,適時終止妊娠,降低圍產兒死亡率.
목적 탐토조발형중도자간전기적림상특정급모영예후.방법 선취2009년1월지2011년12월재산동성등주시부유보건원수치적조발형중도자간전기잉부,공126례.근거발병잉주분위3조,A조:잉주＜28주,36례;B조:28주≤잉주＜32주,40례;C조:32주≤잉주＜34주,50례.비교3조적림상특정급모영결국.결과 3조잉부입원시혈압、24h뇨단백정량、혈소판삼수、뇨소담、D-2취체급혈기항분석차이균무통계학의의(균P＞0.05);3조병발증발생솔수발병잉주연장이하강,3조잉부종지임신시병발증적구성차이무통계학의의(P＞0.05);신생인질식A、B、C조례수분별위33(100％)、18(50％)화9(19％),3조간차이유통계학의의.위산인사망솔3조간차이균유통계학의의(균P ＜0.05);기대치료시간,B조기명현장우기타량조,차이균유통계학의의(균P＜0.05),이A、C조차이무통계학의의(P＞0.05).각조환자적분면방식다이부궁산위주.결론 조발형중도자간전기신생인질식화위산인사망솔수발병잉주연장이강저,응급조진단、적겁치료、엄밀감측모태정황,괄시종지임신,강저위산인사망솔.
Objective To explore the clinical characteristics and maternal and infant prognosis of severe precocious preeclampsia complicated with fetal growth retardation.Methods A study was conducted for 126 patients with early onset severe preeclampsia.According to the gestational week (GW) of morbility,they were divided into group A (GW ＜ 28,n =36),group B (28 ≤ GW ＜ 32,n =40) and group C (32 ≤ GW ＜ 34,n =50).And then compare the respective clinical characteristics and the result of mother and infant.Results At admission,no statistical difference existed among 3 groups in blood pressure,blood platelets,24 h urine protein quantity,urea nitrogen,D-2 polymer or serum creatinine (P ＞ 0.05).the rate of complication declined with advancing gestational weeks of morbility in all three groups.And the composition of complication indicated no statistical difference (P ＞ 0.05) ; there existed statistical difference in asphyxia neonatorum and perinatal mortality rates between any two of three groups (P ＜ 0.05 for all).Comparing expectant treatment time and delivery method of three groups,the expectant time of Group B was obviously longer than those of the other two,both indicated statistical difference (P ＜ 0.05).However,the difference had no statistical significance between groups A and C (P ＞ 0.05).And uterine-incision delivery was the major delivery mode among all three groups.Conclusion The rates of asphyxia neonatorum and perinatal mortality decline with advancing gestational weeks of morbility in cases of severe precocious preeclampsia complicated with fetal growth retardation.Therefore,for reducing the perinatal mortality rate,proper measures include early diagnosis,active treatment,close supervision of mother and fetal conditions and termination of gestation when necessary.
