中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2014年
38期
2973-2976
,共4页
伍颖欣%贺白婷%严惠婵%洪佳旭%罗嘉莹%罗远明
伍穎訢%賀白婷%嚴惠嬋%洪佳旭%囉嘉瑩%囉遠明
오영흔%하백정%엄혜선%홍가욱%라가형%라원명
睡眠呼吸暂停综合征%连续气道正压通气%睡眠呼吸暂停,阻塞性%睡眠呼吸暂停,中枢性%治疗效果
睡眠呼吸暫停綜閤徵%連續氣道正壓通氣%睡眠呼吸暫停,阻塞性%睡眠呼吸暫停,中樞性%治療效果
수면호흡잠정종합정%련속기도정압통기%수면호흡잠정,조새성%수면호흡잠정,중추성%치료효과
Sleep apnea syndromes%Continuous positive airway pressure%Sleep apnea,obstructive%Sleep apnea,central%Treatment outcome
目的 探讨持续气道正压通气(CPAP)对混合性睡眠呼吸暂停(MSA)事件的疗效.方法 选择2011年7月至2013年5月间于广州呼吸疾病研究所睡眠中心经全夜多导睡眠图(PSG)监测发现MSA事件＞10次/h的睡眠呼吸暂停患者21例.其中10例单纯依靠常规PSG诊断(常规PSG组),另11例在常规PSG监测后加用食道电极记录膈肌肌电对MSA事件进一步确诊(膈肌肌电组).所有患者均在PSG监测下进行人工压力滴定并用所滴定的压力治疗,观察CPAP对MSA事件的疗效.结果 常规PSG组平均CPAP治疗压力与膈肌肌电组相似[(8.1±2.2)比(8.9±1.5)cmH2O,1 cmH2O =0.098 kPa].两组患者经CPAP治疗后呼吸暂停低通气指数(AHI)均有显著下降,常规PSG组从治疗前的62.2(54.7,71.4)次/h降至治疗后的6.9(3.5,10.2)次/h;膈肌肌电组从治疗前的71.3(59.5,79.5)次/h降至治疗后的1.5(0.5,5.5)次/h(均P＜0.01).CPAP能有效消除MSA事件.常规PSG组和膈肌肌电组治疗后的MSA均显著低于治疗前[0.1(0.0,0.4)比29.6(19.6,32.4)次/h和0.0(0.0,0.2)比18.1(9.1,19.3)次/h](均P＜0.01).结论 CPAP治疗能够有效消除睡眠呼吸暂停患者的MSA事件.
目的 探討持續氣道正壓通氣(CPAP)對混閤性睡眠呼吸暫停(MSA)事件的療效.方法 選擇2011年7月至2013年5月間于廣州呼吸疾病研究所睡眠中心經全夜多導睡眠圖(PSG)鑑測髮現MSA事件＞10次/h的睡眠呼吸暫停患者21例.其中10例單純依靠常規PSG診斷(常規PSG組),另11例在常規PSG鑑測後加用食道電極記錄膈肌肌電對MSA事件進一步確診(膈肌肌電組).所有患者均在PSG鑑測下進行人工壓力滴定併用所滴定的壓力治療,觀察CPAP對MSA事件的療效.結果 常規PSG組平均CPAP治療壓力與膈肌肌電組相似[(8.1±2.2)比(8.9±1.5)cmH2O,1 cmH2O =0.098 kPa].兩組患者經CPAP治療後呼吸暫停低通氣指數(AHI)均有顯著下降,常規PSG組從治療前的62.2(54.7,71.4)次/h降至治療後的6.9(3.5,10.2)次/h;膈肌肌電組從治療前的71.3(59.5,79.5)次/h降至治療後的1.5(0.5,5.5)次/h(均P＜0.01).CPAP能有效消除MSA事件.常規PSG組和膈肌肌電組治療後的MSA均顯著低于治療前[0.1(0.0,0.4)比29.6(19.6,32.4)次/h和0.0(0.0,0.2)比18.1(9.1,19.3)次/h](均P＜0.01).結論 CPAP治療能夠有效消除睡眠呼吸暫停患者的MSA事件.
목적 탐토지속기도정압통기(CPAP)대혼합성수면호흡잠정(MSA)사건적료효.방법 선택2011년7월지2013년5월간우엄주호흡질병연구소수면중심경전야다도수면도(PSG)감측발현MSA사건＞10차/h적수면호흡잠정환자21례.기중10례단순의고상규PSG진단(상규PSG조),령11례재상규PSG감측후가용식도전겁기록격기기전대MSA사건진일보학진(격기기전조).소유환자균재PSG감측하진행인공압력적정병용소적정적압력치료,관찰CPAP대MSA사건적료효.결과 상규PSG조평균CPAP치료압력여격기기전조상사[(8.1±2.2)비(8.9±1.5)cmH2O,1 cmH2O =0.098 kPa].량조환자경CPAP치료후호흡잠정저통기지수(AHI)균유현저하강,상규PSG조종치료전적62.2(54.7,71.4)차/h강지치료후적6.9(3.5,10.2)차/h;격기기전조종치료전적71.3(59.5,79.5)차/h강지치료후적1.5(0.5,5.5)차/h(균P＜0.01).CPAP능유효소제MSA사건.상규PSG조화격기기전조치료후적MSA균현저저우치료전[0.1(0.0,0.4)비29.6(19.6,32.4)차/h화0.0(0.0,0.2)비18.1(9.1,19.3)차/h](균P＜0.01).결론 CPAP치료능구유효소제수면호흡잠정환자적MSA사건.
Objective To explore the efficacies of continuous positive airway pressure (CPAP) for mixed sleep apnea (MSA) events in patients with sleep apnea.Methods A total of 21 patients with sleep apnea whose MSA events ＞ 10 events/h on overnight polysomnography (PSG) were studied.They were selected from the Sleep Center,Guangzhou Institute of Respiratory Disease.Ten of them were diagnosed only by conventional polysomnography (PSG group) while the diagnosis of another 11 patients was further confirmed by diaphragm electromyogram (EMG) (EMG group).All of them were treated by CPAP titrated manually on PSG.Results Manual CPAP titrating pressure in PSG group was (8.1 ± 2.2) cmH2O (1 cmH2O =0.098 kPa) and it was similar to that in EMG group ((8.9 ± 1.5) cmH2O).Apnea-hypopnea index (AHI) decreased significantly after CPAP in both PSG group (6.9 (3.5,10.2) vs 62.2 (54.7,71.4) events/h) and EMG group (1.5 (0.5,5.5) vs 71.3 (59.5,79.5) events/h) (both P ＜0.01).CPAP could eliminate MSA diagnosed either by conventional PSG (0.1 (0.0,0.4) vs 29.6 (19.6,32.4)events/h) or by diaphragm EMG (0.0 (0.0,0.2) vs 18.1 (9.1,19.3) events/h) (both P ＜ 0.01).Conclusion CPAP can effectively treat MSA events in patients with sleep apnea.
