中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2014年
41期
3229-3233
,共5页
矫毓娟%张伟赫%李小璇%汪伟%刘蕾%张志勇%刘尊敬%汪仁斌%谢晟
矯毓娟%張偉赫%李小璇%汪偉%劉蕾%張誌勇%劉尊敬%汪仁斌%謝晟
교육연%장위혁%리소선%왕위%류뢰%장지용%류존경%왕인빈%사성
脊髓病%视神经脊髓炎%水通道蛋白4%多发性硬化%磁共振成像
脊髓病%視神經脊髓炎%水通道蛋白4%多髮性硬化%磁共振成像
척수병%시신경척수염%수통도단백4%다발성경화%자공진성상
Spinal cord diseases%Neuromyelitis optica%Aquaporin 4%Multiple sclerosis%Magnetic resonance imaging
目的 探讨长节段脊髓病变(LESCL)的病因及影像学特征.方法 连续收集中日友好医院神经内科2011年1月至2013年8月收治的LESCL患者,进行统计并做病因学及MRI特征分析.结果 51例患者中,视神经脊髓炎谱系疾病(NMOSD) 25例,孤立性长节段脊髓炎6例,亚急性联合变性4例,多发性硬化(MS)、副肿瘤性脊髓病变、脊髓前动脉综合征各3例,急性播散性脑脊髓炎和硬脊膜动静脉瘘各2例,脊髓转移瘤、白血病脊髓浸润以及脊髓中央管扩张各1例.NMOSD多是脊髓中心为主的横贯性、纵向延伸的连续性长T2病变,急性期脊髓肿胀明显,增强扫描可见部分强化;其他疾病的MRI表现也各有特点.结论 LESCL的病因复杂,每组疾病的MRI表现虽特异性有限,但仍在一定程度上有助于病因确立.
目的 探討長節段脊髓病變(LESCL)的病因及影像學特徵.方法 連續收集中日友好醫院神經內科2011年1月至2013年8月收治的LESCL患者,進行統計併做病因學及MRI特徵分析.結果 51例患者中,視神經脊髓炎譜繫疾病(NMOSD) 25例,孤立性長節段脊髓炎6例,亞急性聯閤變性4例,多髮性硬化(MS)、副腫瘤性脊髓病變、脊髓前動脈綜閤徵各3例,急性播散性腦脊髓炎和硬脊膜動靜脈瘺各2例,脊髓轉移瘤、白血病脊髓浸潤以及脊髓中央管擴張各1例.NMOSD多是脊髓中心為主的橫貫性、縱嚮延伸的連續性長T2病變,急性期脊髓腫脹明顯,增彊掃描可見部分彊化;其他疾病的MRI錶現也各有特點.結論 LESCL的病因複雜,每組疾病的MRI錶現雖特異性有限,但仍在一定程度上有助于病因確立.
목적 탐토장절단척수병변(LESCL)적병인급영상학특정.방법 련속수집중일우호의원신경내과2011년1월지2013년8월수치적LESCL환자,진행통계병주병인학급MRI특정분석.결과 51례환자중,시신경척수염보계질병(NMOSD) 25례,고립성장절단척수염6례,아급성연합변성4례,다발성경화(MS)、부종류성척수병변、척수전동맥종합정각3례,급성파산성뇌척수염화경척막동정맥루각2례,척수전이류、백혈병척수침윤이급척수중앙관확장각1례.NMOSD다시척수중심위주적횡관성、종향연신적련속성장T2병변,급성기척수종창명현,증강소묘가견부분강화;기타질병적MRI표현야각유특점.결론 LESCL적병인복잡,매조질병적MRI표현수특이성유한,단잉재일정정도상유조우병인학립.
Objective To explore the etiologies and imaging features of longitudinally extensive spinal cord lesion (LESCL).Methods The etiologies and magnetic resonance (MR) imaging features of 51 hospitalized LESCL patients from January 2011 to August 2013 were reviewed and retrospectively analyzed.Results Among them,the causes were neuromyelitis optica spectrum disorder (NMOSD,n =25),isolated longitudinally extensive transverse myelitis (n =6),subacute combined degeneration (n =4),multiple sclerosis (MS,n =3),paraneoplastic myelopathy (n =3),anterior spinal artery syndrome (n =3),acute disseminated encephalomyelitis (n =2),spinal dural arteriovenous fistula (n =2),intramedullary spinal cord metastasis (n =1),myelopathic leukemia (n =1) and syringomyelus (n =1).For MR imaging,at least one lesion of each patient presented continuously longitudinal profile and whole-length spinal cord was involved in 11 patients.Conclusion LESCL may be caused by various diseases.And the imaging features may aid its diagnosis despite a lack of specificity.
