中华医学科研管理杂志
中華醫學科研管理雜誌
중화의학과연관리잡지
ZHONGHUA YIXUE KEYAN GUANLI ZAZHI CHINESE JOURNAL OF MEDICAL SCIENCE RESEARCH MANAGEMENT
2013年
4期
281-284
,共4页
陈思%肖林%任骁方%金恩忠
陳思%肖林%任驍方%金恩忠
진사%초림%임효방%금은충
黄斑厚度%青少年%屈光状态%光相干断层成像
黃斑厚度%青少年%屈光狀態%光相榦斷層成像
황반후도%청소년%굴광상태%광상간단층성상
Macular thickness%Children%refraction%Optical coherence tomography
目的 探讨国人及亚裔黄种青少年黄斑厚度正常值,为该人群黄斑厚度异常相关疾病的诊断提供参考.方法 检索万方、CNKI、Pubmed、Medline等中英文数据库,应用google scholar搜索引擎对文献进行补充,对国人及亚裔黄种青少年人群黄斑厚度研究的相关文献进行筛选并采用自制表格进行数据提取,通过多个小样本均数、标准差的合并公式,求出各研究黄斑区的合并均数、合并标准差,采纳正常国人黄斑厚度值作为参考.结果 文献筛选后最终对12篇文献进行数据合并.合并结果为黄斑中心凹最小厚度、黄斑中心凹(1 mm直径区)平均厚度分别为143.89±17.32 μm(n=2062眼)、181.60±17.93 μm(n=1974眼).最终将以上两个区域及黄斑旁中心凹1~3 mm直径区、3~6 mm直径区各4个象限厚度的数据合并值与成年国人相应区域黄斑厚度值进行比较.按年龄分层进一步分析青少年黄斑厚度特点.结论 正常国人及亚裔黄种人青少年黄斑不同区域厚度值与成人存在差别,儿童黄斑厚度随年龄的变化趋势与成人不同,因此临床诊断青少年黄斑厚度异常相关疾病时应综合考虑年龄、屈光度、眼轴、种族、性别等因素.此外,更合理的正常参考值范围尚待大样本横断面研究提出.
目的 探討國人及亞裔黃種青少年黃斑厚度正常值,為該人群黃斑厚度異常相關疾病的診斷提供參攷.方法 檢索萬方、CNKI、Pubmed、Medline等中英文數據庫,應用google scholar搜索引擎對文獻進行補充,對國人及亞裔黃種青少年人群黃斑厚度研究的相關文獻進行篩選併採用自製錶格進行數據提取,通過多箇小樣本均數、標準差的閤併公式,求齣各研究黃斑區的閤併均數、閤併標準差,採納正常國人黃斑厚度值作為參攷.結果 文獻篩選後最終對12篇文獻進行數據閤併.閤併結果為黃斑中心凹最小厚度、黃斑中心凹(1 mm直徑區)平均厚度分彆為143.89±17.32 μm(n=2062眼)、181.60±17.93 μm(n=1974眼).最終將以上兩箇區域及黃斑徬中心凹1~3 mm直徑區、3~6 mm直徑區各4箇象限厚度的數據閤併值與成年國人相應區域黃斑厚度值進行比較.按年齡分層進一步分析青少年黃斑厚度特點.結論 正常國人及亞裔黃種人青少年黃斑不同區域厚度值與成人存在差彆,兒童黃斑厚度隨年齡的變化趨勢與成人不同,因此臨床診斷青少年黃斑厚度異常相關疾病時應綜閤攷慮年齡、屈光度、眼軸、種族、性彆等因素.此外,更閤理的正常參攷值範圍尚待大樣本橫斷麵研究提齣.
목적 탐토국인급아예황충청소년황반후도정상치,위해인군황반후도이상상관질병적진단제공삼고.방법 검색만방、CNKI、Pubmed、Medline등중영문수거고,응용google scholar수색인경대문헌진행보충,대국인급아예황충청소년인군황반후도연구적상관문헌진행사선병채용자제표격진행수거제취,통과다개소양본균수、표준차적합병공식,구출각연구황반구적합병균수、합병표준차,채납정상국인황반후도치작위삼고.결과 문헌사선후최종대12편문헌진행수거합병.합병결과위황반중심요최소후도、황반중심요(1 mm직경구)평균후도분별위143.89±17.32 μm(n=2062안)、181.60±17.93 μm(n=1974안).최종장이상량개구역급황반방중심요1~3 mm직경구、3~6 mm직경구각4개상한후도적수거합병치여성년국인상응구역황반후도치진행비교.안년령분층진일보분석청소년황반후도특점.결론 정상국인급아예황충인청소년황반불동구역후도치여성인존재차별,인동황반후도수년령적변화추세여성인불동,인차림상진단청소년황반후도이상상관질병시응종합고필년령、굴광도、안축、충족、성별등인소.차외,경합리적정상삼고치범위상대대양본횡단면연구제출.
Objective To study the normal macular thickness in children provide reference for the diagnosis of macular thickness abnormity in teenagers.Methods Databases including Wanfang,Pubmed and some others were searched for studies on macular thickness in Asian children.Data of macular thickness were extracted and were merged into only one by formulae.Results 12 studies were enrolled.The mean foveal minimum and central macular thickness were 143.89±17.32μm(n=2062 eyes) and 181.60±17.93μm(n=1974 eyes),respectively.The eight areas of inner circle (1~3mm diameter) and the outer circle (3~6mm diameter) macular thickness were also calculated.The central macular area seemed thicker in pre-school children than school children.Conclusion Chidren's macular thickness have different characteristic from adults',so it is important to take age,refraction,axial length,race and sex into account before making an abnormal macular thickness diagnosis.Meanwhile,a large sample of population-based cross-sectional study in children is necessary for a more effective standard.