CAJ | 학술논문

目的探讨1064 nm长脉冲激光联合曲安奈德局部注射治疗瘢痕疙瘩的临床疗效.方法将78例患者随机分为两组:治疗组41例,采用1064 nm长脉冲钕∶钇-铝-石榴石(Nd∶ YAG)激光联合曲安奈德注射液局部注射；对照组37例,仅局部注射曲安奈德.复诊每隔3周1次,未痊愈及复发者继续治疗,4次为1个疗程,共观察2个疗程.分别于第1、第2个疗程结束后判断疗效和不良反应,随访1年以验证复发情况.结果第1个疗程后治疗组痊愈率21.95％,有效率73.17％；对照组痊愈率10.81％,有效率45.95％,治疗组有效率明显高于对照组(P＜0.05)；第2个疗程后治疗组痊愈率70.73％,有效率100％,对照组痊愈率45.95％,有效率83.78％,治疗组痊愈率及有效率均明显高于对照组(P＜0.05).结论长脉冲1064 nm激光联合曲安奈德局部注射治疗瘢痕疙瘩见效快,副作用小、治愈率高,疗效确切.
목적 탐토1064 nm장맥충격광연합곡안내덕국부주사치료반흔흘탑적림상료효.방법 장78례환자수궤분위량조:치료조41례,채용1064 nm장맥충녀∶을-려-석류석(Nd∶ YAG)격광연합곡안내덕주사액국부주사；대조조37례,부국부주사곡안내덕.복진매격3주1차,미전유급복발자계속치료,4차위1개료정,공관찰2개료정.분별우제1、제2개료정결속후판단료효화불량반응,수방1년이험증복발정황.결과 제1개료정후치료조전유솔21.95％,유효솔73.17％；대조조전유솔10.81％,유효솔45.95％,치료조유효솔명현고우대조조(P＜0.05)；제2개료정후치료조전유솔70.73％,유효솔100％,대조조전유솔45.95％,유효솔83.78％,치료조전유솔급유효솔균명현고우대조조(P＜0.05).결론 장맥충1064 nm격광연합곡안내덕국부주사치료반흔흘탑견효쾌,부작용소、치유솔고,료효학절.
Objective To evaluate the clinical efficacy of long-pulsed 1064 nm Nd ∶ YAG laser combined with intralesional injection of triamcinolone in the treatment of keloids.Methods A total of 78 cases were randomly divided into two groups.The treatment group was treated with long-pulsed 1064 nm Nd ∶ YAG laser combined with intralesional injection of triamcinolone.The control group was only given intralesional injection of triamcinolone.The efficacy and adverse reactions were determined at the end of the first and the second course,respectively,and follow-up for one year was conducted in order to observe the recurrence.Results When the first course was over,cure rate of 21.95 ％ and efficiency rate of 73.17 ％ were observed in the treatment group,while they were 10.81％ and 45.95 ％,respectively,in the control group; the efficacy rate was statistically significant different in these two groups (P＜0.05).After two courses,cure rate of 70.73 ％ and efficiency rate of 100 ％ were observed in the treatment group while they were 45.95 ％ and 83.78 ％,respectively,in the control group,showing that both of the rates were statistically higher in the treatment group (P＜0.05).Conclusions Compared to intralesional injection of triamcinolone,long-pulsed 1064 nm Nd ∶ YAG laser combined with injection of triamcinolone has a more satisfactory effect on keloids.