CAJ | 학술논문

目的探讨年龄因素对90锶-90钇(90Sr-90Y)敷贴器治疗皮肤血管瘤疗效的影响.方法对224例不同年龄段婴幼儿和儿童皮肤血管瘤患者进行90Sr-90Y敷贴器治疗,回顾性分析了其疗效与患者年龄的关系.结果 (1)在1个月至＜1岁组和1至＜5岁组之间,1个月至＜1岁组和5～10岁组之间,1至＜5岁组和5～10岁组之间,其疗效差异均有统计学意义(P＜0.05)；随着患者年龄的增长,其痊愈率逐渐降低,而其显效率、好转率和无效率却逐渐升高.(2)90Sr-90Y敷贴器治疗后痊愈或显效的199例患者中,在1个月至＜1岁组和1至＜5岁组之间,1个月至＜1岁组和5～10岁组之间,其疗程分布差异均有统计学意义(P＜0.05)；在1至＜5岁组和5～10岁组之间,其疗程分布差异无统计学意义(P＞0.05).随着患者年龄的增长,其所需疗程数呈增加的趋势.结论患者的年龄是影响90Sr-90Y敷贴器治疗皮肤血管瘤疗效的因素,患者年龄越小则疗效越好、疗程越短、射线的不良反应越轻.
목적 탐토년령인소대90송-90을(90Sr-90Y)부첩기치료피부혈관류료효적영향.방법 대224례불동년령단영유인화인동피부혈관류환자진행90Sr-90Y부첩기치료,회고성분석료기료효여환자년령적관계.결과 (1)재1개월지＜1세조화1지＜5세조지간,1개월지＜1세조화5～10세조지간,1지＜5세조화5～10세조지간,기료효차이균유통계학의의(P＜0.05)；수착환자년령적증장,기전유솔축점강저,이기현효솔、호전솔화무효솔각축점승고.(2)90Sr-90Y부첩기치료후전유혹현효적199례환자중,재1개월지＜1세조화1지＜5세조지간,1개월지＜1세조화5～10세조지간,기료정분포차이균유통계학의의(P＜0.05)；재1지＜5세조화5～10세조지간,기료정분포차이무통계학의의(P＞0.05).수착환자년령적증장,기소수료정수정증가적추세.결론 환자적년령시영향90Sr-90Y부첩기치료피부혈관류료효적인소,환자년령월소칙료효월호、료정월단、사선적불량반응월경.
Objective To explore the influence of age factor on the treatment of cutaneous hemangioma with (90Sr-90Y) applicator.Methods A total of 224 babies and children of different ages with cutaneous hemangioma were treated by using 90Sr-90 Y applicator.Then,the relation between their therapeutic effects and ages were analyzed respectively.Results The differences in the therapeutic effect between group of one month to less than one year and group of one to less than five years,and group of one month to less than one year and group of five to ten years,and between group of one to less than five ages and group of five to ten years (P＜0.05),were statistically significant.With an increase of the age,the recovery rate gradually decreased,but their effective rate,improvement rate and ineffective rate increased.In the 199 well-healed or effective patients,the differences in the distribution of treatment course between group of one month to less than one year and group of one to less than five years,and group of one month to less than one year and group of five to ten years,were statistically significant (P＜0.05); but the difference in the distribution of treatment course between group of one to less than five ages and group of five to ten years was not statistically significant (P＞0.05).The number of treatment course presented an increased tendency with an increase of the age for patients.Conclusions The age of patients is a factor influencing the therapeutic effect on cutaneous hemangioma with 90 Sr-90Y applicator.The younger the patients,the better their therapeutic effects,the shorter their courses of treatment,and the smaller the adverse reaction of beta ray.