CAJ | 학술논문

目的临床观察聚桂醇注射液局部瘤体内注射治疗婴幼儿皮肤血管瘤的疗效.方法对30例血管瘤患儿局部瘤体内注射硬化剂——聚桂醇注射液,定期观察和记录血管瘤大小、质地、颜色的变化,并随时处理治疗过程中出现的不良反应.根据瘤体消退情况确定治疗次数.治疗结束后6个月,按4级评分法对疗效进行评价.结果 30例患儿均完成治疗全程,其中达到I级疗效者2例(6.7％),Ⅱ级疗效者4例(13.3％),Ⅲ级疗效者5例(16.7％),Ⅳ级疗效者19例(63.3％).瘤体直径越小,硬化剂注射治疗的次数越少,且治疗效果越好.早期积极给予聚桂醇硬化剂治疗的效果较好.所有患儿随访6个月均未复发,也未出现严重的不良反应.结论聚桂醇硬化疗法是一种安全、有效地治疗婴幼儿血管瘤的方法.
목적 림상관찰취계순주사액국부류체내주사치료영유인피부혈관류적료효.방법 대30례혈관류환인국부류체내주사경화제——취계순주사액,정기관찰화기록혈관류대소、질지、안색적변화,병수시처리치료과정중출현적불량반응.근거류체소퇴정황학정치료차수.치료결속후6개월,안4급평분법대료효진행평개.결과 30례환인균완성치료전정,기중체도I급료효자2례(6.7％),Ⅱ급료효자4례(13.3％),Ⅲ급료효자5례(16.7％),Ⅳ급료효자19례(63.3％).류체직경월소,경화제주사치료적차수월소,차치료효과월호.조기적겁급여취계순경화제치료적효과교호.소유환인수방6개월균미복발,야미출현엄중적불량반응.결론 취계순경화요법시일충안전、유효지치료영유인혈관류적방법.
Objective To investigate the effect of intralesional lauromacrogol therapy on infantile hemangioma.Methods 30 cases all received intralesional injection of lauromacrogol.The changes of tumor size,texture and color were monitored and recorded.The adverse effects after medication were observed and managed accordingly.The adverse effects after medication were observed.The times of treatment were determined according to degree of reduction of tumor volume.To assess the efficacy,a 4 scales system was adopted.Results All patients had completed the treatment and followup.The overall response was scale Ⅰ in 2 cases (6.7 ％),scale Ⅱ efficacy in 4 patients (13.3 ％),scale Ⅲ efficacy in 5 cases (16.7 ％) and scale Ⅳ in 19 cases (63.3 ％).The smaller the tumor,the fewer the times of treatment,and the better the results.The effects of treatment were better if patient could be treated by intralesional lauromacrogol therapy in early stage.No severe adverse effects were observed during 6 months of follow-up.Conclusions Intralesional injection of lauromacrogol sclerotherapy is a safe and effective way to treat infantile hemangioma.