CAJ | 학술논문

目的分析北京市女性居民乳腺癌发病与经济发展水平的相关性.方法利用北京肿瘤登记处以人群为基础的肿瘤发病监测数据库,提取2001-2010年北京市户籍居民女性乳腺癌发病数据,共计28 184例,覆盖女性人口58 427 396人年.计算北京市女性乳腺癌各年度发病率、世界人口标化发病率、各区县女性乳腺癌的中位发病年龄、平均发病年龄及发病高峰年龄段.应用JoinPoint软件对发病率变化趋势进行分析,计算世界人口标化年度变化率(APC).利用《北京市统计年鉴》中发布的1991-2000年北京市工业总产值、居民平均工资水平、食品支出水平以及各区县平均工资水平等数据,分析女性乳腺癌发病率、发病年龄与10年前经济发展水平各要素的相关性.结果北京市女性居民乳腺癌的发病率由2001年的32.03/10万增长至2010年的58.10/10万,增长率为81.39％,经世界人口构成标化后,年平均增长5.76％(APC=5.76％,P＜0.05).2001-2010年,北京市女性居民乳腺癌发病率与1991-2000年北京市工业总产值、平均工资水平及居民食品支出水平均相关(r值分别为0.928、0.957和0.982,均P＜0.05).2001-2010年,北京市女性居民乳腺癌的中位发病年龄、平均发病年龄及发病高峰年龄段与1991-2000年北京市各区县居民平均工资水平均相关(r值分别为0.806、0.785和0.754,均P＜0.05).结论北京市女性居民乳腺癌发病率的增长与社会经济发展水平、尤其是食品消费支出水平呈正相关;经济发展程度越高,女性乳腺癌的发病年龄高峰越往后推迟.
목적 분석북경시녀성거민유선암발병여경제발전수평적상관성.방법 이용북경종류등기처이인군위기출적종류발병감측수거고,제취2001-2010년북경시호적거민녀성유선암발병수거,공계28 184례,복개녀성인구58 427 396인년.계산북경시녀성유선암각년도발병솔、세계인구표화발병솔、각구현녀성유선암적중위발병년령、평균발병년령급발병고봉년령단.응용JoinPoint연건대발병솔변화추세진행분석,계산세계인구표화년도변화솔(APC).이용《북경시통계년감》중발포적1991-2000년북경시공업총산치、거민평균공자수평、식품지출수평이급각구현평균공자수평등수거,분석녀성유선암발병솔、발병년령여10년전경제발전수평각요소적상관성.결과 북경시녀성거민유선암적발병솔유2001년적32.03/10만증장지2010년적58.10/10만,증장솔위81.39％,경세계인구구성표화후,년평균증장5.76％(APC=5.76％,P＜0.05).2001-2010년,북경시녀성거민유선암발병솔여1991-2000년북경시공업총산치、평균공자수평급거민식품지출수평균상관(r치분별위0.928、0.957화0.982,균P＜0.05).2001-2010년,북경시녀성거민유선암적중위발병년령、평균발병년령급발병고봉년령단여1991-2000년북경시각구현거민평균공자수평균상관(r치분별위0.806、0.785화0.754,균P＜0.05).결론 북경시녀성거민유선암발병솔적증장여사회경제발전수평、우기시식품소비지출수평정정상관;경제발전정도월고,녀성유선암적발병년령고봉월왕후추지.
Objective To explore the relationship between female breast cancer incidence and the socioeconomic status in Beijing.Methods The data of female breast cancer patients of Beijing residents diagnosed between 2001 and 2010 were sorted from the population-based surveillance database of Beijing Cancer Registry.28,184 cases were included,covering 58,427,396 female person-years.Incidence rates,rates adjusted by world population in each year,mean and median age at diagnosis and the peak age group were calculated.JoinPoint software was applied to calculate the incidence trend and the annual percentage of changing (APC).Using the data from the Beijing Statistical Yearbook in 1991-2000,we calculated the gross output value of industry,the average wage of Beijing residents,the food expenditure level and the average wage in different districts in Beijing.The relationship between female breast cancer incidence,the average age (mean,median and the peak age groups) at diagnosis and the socioeconomic status in the last 10 years was also calculated.Results From 2001 to 2010,the incidence rate of female breast cancer in Beijing rose from 32.03/100 000 to 58.10/100 000,a total increase of 81.39％ over the last 10 years and the annual percentage change was 5.76％,after adjusted by world population (APC =5.76％,P ＜ 0.05).The relationships between female breast cancer incidence from 2001-2010 and the gross output value of industry,the average wage of Beijing residents,the food expenditure level in 1991-2000 were significant (P ＜ 0.05).The Pearson correlation coefficients were 0.928,0.957,and 0.982,respectively.In terms of the data in different districts in Beijing,the relationships between the average age (mean,median and the peak age group) in 2001-2010 and the average wage of Beijing residence in 1991-2000 were also significant with a correlation coefficient of 0.806,0.785 and 0.754,respectively (P ＜ 0.05).Conclusions The increase of female breast cancer incidence rate in Beijing is positively correlated with the socioeconomic status,especially with the food expenditure level of Beijing residents over the last 10 years.The higher the economic development,the peak age of onset of female breast cancer is more postponed.