CAJ | 학술논문

目的探讨1％聚桂醇注射液治疗面部血管瘤及血管畸形的临床疗效.方法 2009年9月至2011年11月,临床治疗55例不同类型的颜面部难治性血管瘤及血管畸形患者,男20例,女35例,年龄为1个月至30岁,瘤体面积为1.0cm×(0.5～5.0) cm×10.0 cm,采用1％聚桂醇瘤内注射治疗,根据患者的年龄、瘤体大小和深度决定用药浓度、剂量和注射次数,个体1次最大剂量不超过10 ml,两次注射间隔为1～4周.结果经3～16个月随访,治愈41例,基本治愈9例,有效5例.2例出现局部皮肤破溃,换药后创面愈合.结论 1％聚桂醇作为一种硬化剂治疗颜面部难治性血管性疾病,安全有效,且简单易行.
목적 탐토1％취계순주사액치료면부혈관류급혈관기형적림상료효.방법 2009년9월지2011년11월,림상치료55례불동류형적안면부난치성혈관류급혈관기형환자,남20례,녀35례,년령위1개월지30세,류체면적위1.0cm×(0.5～5.0) cm×10.0 cm,채용1％취계순류내주사치료,근거환자적년령、류체대소화심도결정용약농도、제량화주사차수,개체1차최대제량불초과10 ml,량차주사간격위1～4주.결과 경3～16개월수방,치유41례,기본치유9례,유효5례.2례출현국부피부파궤,환약후창면유합.결론 1％취계순작위일충경화제치료안면부난치성혈관성질병,안전유효,차간단역행.
Objective To investigate the clinical effect of 1％ lauromacrogol for the treatment of facial refractory hemangioma and vascular malformation.Methods From Sept 2009 to Nov 2011,55 patients (20 male,35 female,1 month to 30 years) with different types of facial hemangioma and vascular malformation about 1.0 cm × (0.5-5.0) cm × 10.0 cm in size,underwent 1％ lauromacrogol intratumor injection therapy.Generally,the injection dose,concentration,frequency were determined by the age of the patients,the volume and depth of the lesion.The dose was limited to 10 mg every time.The injection interval is 1-4 weeks.Results After followed up for 3-16 months,41 cases were cured,9 cases were greatly improved,and 5 were partially improved.Skin necrosis happened in only 2 cases.Conclusions Lauromacrogol is safe,simple and effective as a sderosing agent for the treatment of facial refractory hemangioma and vascular malformation.It provides a new and alternative way for the treatment of facial refractory hemangioma and vascular malformation.