中华整形外科杂志
中華整形外科雜誌
중화정형외과잡지
CHINESE JOURNAL OF PLASTIC SURGERY
2013年
5期
356-361
,共6页
乳房再造术%脱细胞真皮基质%Meta分析
乳房再造術%脫細胞真皮基質%Meta分析
유방재조술%탈세포진피기질%Meta분석
Breast reconstruction%Acellular dermal matrix%Meta-analysis
目的 对在扩张器/假体乳房再造术中应用脱细胞真皮基质(acellular dermal matrix,ADM)是否增加术后并发症进行探讨,以为临床应用提供初步依据.方法 计算机检索2010年1月至2012年10月Pubmed、EMbase、Science Direct、中国生物医学文献数据库和中国期刊网全文数据库中发表的文献,设定文献纳入条件,对符合条件的文献进行并发症相关数据导出,然后使用Stata 12.0进行Meta分析.结果 共有10篇文献被纳入分析.与对照组相比,ADM组总并发症、感染,血肿/血清肿及扩张器/假体取出发生率的比值比(OR)分别为1.51(P =0.038)、1.91(P=0.032)、1.80(P =0.005)和2.37(P =0.138).结论 在扩张器/假体的乳房再造术中,使用ADM对血肿/血清肿的发生有促进作用,并有增加感染率及总并发症发生率的趋势.
目的 對在擴張器/假體乳房再造術中應用脫細胞真皮基質(acellular dermal matrix,ADM)是否增加術後併髮癥進行探討,以為臨床應用提供初步依據.方法 計算機檢索2010年1月至2012年10月Pubmed、EMbase、Science Direct、中國生物醫學文獻數據庫和中國期刊網全文數據庫中髮錶的文獻,設定文獻納入條件,對符閤條件的文獻進行併髮癥相關數據導齣,然後使用Stata 12.0進行Meta分析.結果 共有10篇文獻被納入分析.與對照組相比,ADM組總併髮癥、感染,血腫/血清腫及擴張器/假體取齣髮生率的比值比(OR)分彆為1.51(P =0.038)、1.91(P=0.032)、1.80(P =0.005)和2.37(P =0.138).結論 在擴張器/假體的乳房再造術中,使用ADM對血腫/血清腫的髮生有促進作用,併有增加感染率及總併髮癥髮生率的趨勢.
목적 대재확장기/가체유방재조술중응용탈세포진피기질(acellular dermal matrix,ADM)시부증가술후병발증진행탐토,이위림상응용제공초보의거.방법 계산궤검색2010년1월지2012년10월Pubmed、EMbase、Science Direct、중국생물의학문헌수거고화중국기간망전문수거고중발표적문헌,설정문헌납입조건,대부합조건적문헌진행병발증상관수거도출,연후사용Stata 12.0진행Meta분석.결과 공유10편문헌피납입분석.여대조조상비,ADM조총병발증、감염,혈종/혈청종급확장기/가체취출발생솔적비치비(OR)분별위1.51(P =0.038)、1.91(P=0.032)、1.80(P =0.005)화2.37(P =0.138).결론 재확장기/가체적유방재조술중,사용ADM대혈종/혈청종적발생유촉진작용,병유증가감염솔급총병발증발생솔적추세.
Objective To analyze the effect of acellular dermal matrix (ADM) on complications of breast reconstruction using tissue expander/implant,and to offer preliminary evidences for ADM clinical application.Methods Articles published from Jan.2010 to Oct.2012 were searched in Pubmed,EMbase,Science Direct and CNKI database.Literatures were filtrated according to inclusive criteria.Values were extracted from included literatures; factors regarding complications were collected.Metaanalysis was performed with Stata 12.0.Results 10 researches were included.Comparing to control group,the pooled odds ratio (OR) of overall complications,infections,hematomas/seromas,explantations are 1.51(P=0.038),1.91(P=0.032),1.80(P=0.005) and 2.37 (P=0.138) in ADM group respectively.Conclusions In breast reconstruction using tissue expander/implant,ADM increases the occurrence of hematomas/saromas as well as risks of infections and overall complications.
