中华整形外科杂志
中華整形外科雜誌
중화정형외과잡지
CHINESE JOURNAL OF PLASTIC SURGERY
2013年
6期
453-456
,共4页
侯敏%石广玉%仇巍%张兰成%于天平%柳春明
侯敏%石廣玉%仇巍%張蘭成%于天平%柳春明
후민%석엄옥%구외%장란성%우천평%류춘명
腭裂%生物力学%瘢痕
腭裂%生物力學%瘢痕
악렬%생물역학%반흔
Cleft palate%Biomechanics%Cicatrix
目的 研究兔正常腭黏膜及黏膜瘢痕的生物力学性质,及其应力与应变的关系.方法 建立兔腭裂实验模型,实验组于腭黏膜瘢痕明显的部位切取宽2～3 mm、长约15 mm的黏膜瘢痕,对照组于相同部位切取同样大小的正常腭黏膜,于加载测试仪上做拉伸实验.结果 瘢痕和正常黏膜的弹性模量分别为(24.22±1.31) MPa和(3.32±0.94) MPa,泊松比为0.49,黏膜瘢痕具有较高的弹性模量和强度,而正常黏膜的弹性模量和抗拉强度都有所下降,但瘢痕和正常黏膜的泊松比分别为(0.5±0.06)和(0.49±0.02),显示了生物活体材料的不可压缩性.结论 腭裂术后黏膜瘢痕生物力学性质研究,可为临床腭裂继发上颌发育不全正颌、正畸及牵引成骨治疗提供生物力学指导.
目的 研究兔正常腭黏膜及黏膜瘢痕的生物力學性質,及其應力與應變的關繫.方法 建立兔腭裂實驗模型,實驗組于腭黏膜瘢痕明顯的部位切取寬2～3 mm、長約15 mm的黏膜瘢痕,對照組于相同部位切取同樣大小的正常腭黏膜,于加載測試儀上做拉伸實驗.結果 瘢痕和正常黏膜的彈性模量分彆為(24.22±1.31) MPa和(3.32±0.94) MPa,泊鬆比為0.49,黏膜瘢痕具有較高的彈性模量和彊度,而正常黏膜的彈性模量和抗拉彊度都有所下降,但瘢痕和正常黏膜的泊鬆比分彆為(0.5±0.06)和(0.49±0.02),顯示瞭生物活體材料的不可壓縮性.結論 腭裂術後黏膜瘢痕生物力學性質研究,可為臨床腭裂繼髮上頜髮育不全正頜、正畸及牽引成骨治療提供生物力學指導.
목적 연구토정상악점막급점막반흔적생물역학성질,급기응력여응변적관계.방법 건립토악렬실험모형,실험조우악점막반흔명현적부위절취관2～3 mm、장약15 mm적점막반흔,대조조우상동부위절취동양대소적정상악점막,우가재측시의상주랍신실험.결과 반흔화정상점막적탄성모량분별위(24.22±1.31) MPa화(3.32±0.94) MPa,박송비위0.49,점막반흔구유교고적탄성모량화강도,이정상점막적탄성모량화항랍강도도유소하강,단반흔화정상점막적박송비분별위(0.5±0.06)화(0.49±0.02),현시료생물활체재료적불가압축성.결론 악렬술후점막반흔생물역학성질연구,가위림상악렬계발상합발육불전정합、정기급견인성골치료제공생물역학지도.
Objective To explore biomechanical properties and stress-strain of mucosa scars after cleft palate surgery.Methods After the model of mucosa scars was made,the mucosa scars and normal mucosa were excised and examined immediately by tensionometry.Results The mucosa scars after cleft palate surgery were compared with normal mucosa.The Poisson' s ratio of mucosa scars and normal mucosa was 0.5 and 0.49,respectively,showing no significant difference between the two groups.The ultimate Young' s modulus of mucosa scars was about 24.22 MPa,however,it declined to 3.32 Mpa in normal mucosa.Conclusions The mucosa scars after cleft palate surgery are biomechanically weaker than normal mucosa.It can be used for further research,such as maxillary orthognathic surgery,distraction osteogenesis,and orthodontic treatment.
