肿瘤研究与临床
腫瘤研究與臨床
종류연구여림상
CANCER RESEARCH AND CLINIC
2009年
9期
591-593
,共3页
庄兢%高阳%夏庆欣%张勇超
莊兢%高暘%夏慶訢%張勇超
장긍%고양%하경흔%장용초
胃肠道间质瘤%临床表现%预后%治疗
胃腸道間質瘤%臨床錶現%預後%治療
위장도간질류%림상표현%예후%치료
Gastrointestinal stromal tumor%Clinical manifestations%Prognosis%Surgical management
目的 探讨胃肠道间质瘤(GIST)的临床表现、诊断和治疗方法以及与预后相关的因素.方法 回顾性分析79例发生于胃的GIST的临床和病理资料,分析影响预后的相关因素.结果 临床表现无特异性,多通过超声内镜、CT、消化道钡餐造影等影像学检查发现肿瘤,明确诊断需通过病理组织学及免疫组化检查,79例中,CD+117 73例 (93%)、CD+34 66例(83%),经手术治疗5年生存率83%,5年无瘤生存率72%.结论 发生于胃的GIST首选治疗方法是手术切除,肿瘤出血、坏死及Fletcher分型是影响预后的重要指标.
目的 探討胃腸道間質瘤(GIST)的臨床錶現、診斷和治療方法以及與預後相關的因素.方法 迴顧性分析79例髮生于胃的GIST的臨床和病理資料,分析影響預後的相關因素.結果 臨床錶現無特異性,多通過超聲內鏡、CT、消化道鋇餐造影等影像學檢查髮現腫瘤,明確診斷需通過病理組織學及免疫組化檢查,79例中,CD+117 73例 (93%)、CD+34 66例(83%),經手術治療5年生存率83%,5年無瘤生存率72%.結論 髮生于胃的GIST首選治療方法是手術切除,腫瘤齣血、壞死及Fletcher分型是影響預後的重要指標.
목적 탐토위장도간질류(GIST)적림상표현、진단화치료방법이급여예후상관적인소.방법 회고성분석79례발생우위적GIST적림상화병리자료,분석영향예후적상관인소.결과 림상표현무특이성,다통과초성내경、CT、소화도패찬조영등영상학검사발현종류,명학진단수통과병리조직학급면역조화검사,79례중,CD+117 73례 (93%)、CD+34 66례(83%),경수술치료5년생존솔83%,5년무류생존솔72%.결론 발생우위적GIST수선치료방법시수술절제,종류출혈、배사급Fletcher분형시영향예후적중요지표.
Objective To investigate the clinical manifestations,diagnosis,prognosis and treatment of gastric stromal tamors(GIST).Methods The Clinical and pathological data including immunohistochemical results of 79 patients with GIST of stomach from Aug 2000 to Aug 2003 were collected,and the clinical and pathological data were analyzed retrospectively. Results The clinical manifestations of GIST were nonspecific.Tumors could be found out by EUS,CT,and barium meal examination.Immunohistochemical staining and pathohistology was necessary for the diagnosis of GIST.In 79 cases GIST,CD117 staining was positive in 93%cases,and CD34 was in 83%.The 5-year survival rate was 83%.The 5-year tumor-free survival rate was 72%.Conclusion Surgical resection iS the standard treatment for non metastatic GIST.Tumors with necrosis,bleeding and high GIST in Fletcher'types are poor prognosis factors.
