中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
5期
33-35
,共3页
妊娠丢失%筛查%抗磷脂抗体
妊娠丟失%篩查%抗燐脂抗體
임신주실%사사%항린지항체
Pregnancy loss%Screening%Antiphospholipid antibodies
目的 探讨妊娠丢失与抗磷脂抗体(APA)[包括抗心磷脂抗体(ACA)和狼疮抗凝抗体(LA)]的关系.方法 观察组为150例有妊娠丢失史的患者,其中分为胚胎停育组(36例)、死胎组(44例)和复发性流产组(70例).对照组为同期120例正常孕妇,分别测定观察组和对照组静脉血清APA水平,并进行对比分析.结果 整个观察组APA、ACA、LA的阳性率均高于对照组,差异有统计学意义(P＜0.05).胚胎停育组与对照组比较,差异无统计学意义(P＞0.05).死胎组和复发性流产组的APA、ACA、LA阳性率分别与对照组比较,差异均有统计学意义(P＜0.05).结论 APA与妊娠丢失有关,尤其对于复发性流产和死胎者.因此,对有不良孕产史的患者常规筛查APA,有利于尽早对因治疗.
目的 探討妊娠丟失與抗燐脂抗體(APA)[包括抗心燐脂抗體(ACA)和狼瘡抗凝抗體(LA)]的關繫.方法 觀察組為150例有妊娠丟失史的患者,其中分為胚胎停育組(36例)、死胎組(44例)和複髮性流產組(70例).對照組為同期120例正常孕婦,分彆測定觀察組和對照組靜脈血清APA水平,併進行對比分析.結果 整箇觀察組APA、ACA、LA的暘性率均高于對照組,差異有統計學意義(P＜0.05).胚胎停育組與對照組比較,差異無統計學意義(P＞0.05).死胎組和複髮性流產組的APA、ACA、LA暘性率分彆與對照組比較,差異均有統計學意義(P＜0.05).結論 APA與妊娠丟失有關,尤其對于複髮性流產和死胎者.因此,對有不良孕產史的患者常規篩查APA,有利于儘早對因治療.
목적 탐토임신주실여항린지항체(APA)[포괄항심린지항체(ACA)화랑창항응항체(LA)]적관계.방법 관찰조위150례유임신주실사적환자,기중분위배태정육조(36례)、사태조(44례)화복발성유산조(70례).대조조위동기120례정상잉부,분별측정관찰조화대조조정맥혈청APA수평,병진행대비분석.결과 정개관찰조APA、ACA、LA적양성솔균고우대조조,차이유통계학의의(P＜0.05).배태정육조여대조조비교,차이무통계학의의(P＞0.05).사태조화복발성유산조적APA、ACA、LA양성솔분별여대조조비교,차이균유통계학의의(P＜0.05).결론 APA여임신주실유관,우기대우복발성유산화사태자.인차,대유불량잉산사적환자상규사사APA,유리우진조대인치료.
Objective To investigate the relationship between history of pregnancy loss and antiphospholipid antibodies (APA),including anticardiolipin (ACA) and lupus anti-coagulant antibodies (LA).Methods One hundred and fifty patients with history of unexplained pregnancy loss as study group and 120 normal nonpregnant women as control group.The study group was further divided into three subgroups:embryo growth arrest (n =36),stillbirth (n =44),and recurrent abortion (n =70)levels of serum APA(including ACA and LA) were determined repectively and analyzed.Results The positive rates of APA,ACA,LA in the study group were significantly higher than those in control group (P ＜ 0.05).The above significance was true in both stillbirth and recurrent abortion groups but not in embryo growth arrest group.Conclusions Levels of serum APA are associated with pregnancy loss,especially about recurrent abortion and stillbirth.We suggest routine screening of serum APA should be performed in patients with history of fetal wastage for the sake of early treatment.
