CAJ | 학술논문

目的分析功能性消化不良患者(FD)的症状与抑郁焦虑状况的相关关系.方法按罗马Ⅲ标准将120例功能性消化不良患者分为餐后不适综合征(PDS)和上腹疼痛综合征(EPS)两组,设立对照组,入组者按标准完成焦虑自评量表(SAS)和抑郁自评量表(SDS).通过SPSS 16.0统计软件分析FD患者的焦虑抑郁状态,以及FD分型、重叠肠易激综合征(IBS)与抑郁焦虑状况的相互关系.结果 ①FD组合并焦虑状态率为63.3％,抑郁率为70％；对照组合并焦虑状态率为19.2％,抑郁率为7.5％,FD组高于对照组,差异有统计学意义(P＜0.05).②PDS组合并焦虑、抑郁状态率分别是69.8％、73.6％,EPS合并焦虑、抑郁状态率为58.2％、67.2％,两组比较差异无统计学意义(P＞0.05).③将所有患者分为无IBS组(81例)与重叠IBS组(39例),无IBS组无焦虑者占51.9％,合并焦虑率者占48.1％；无抑郁率为37.0％,合并抑郁率为63.0％.重叠IBS组无焦虑者占5.1％,合并焦虑者占94.9％；无抑郁率为15.4％,合并抑郁率为84.6％.重叠IBS组合并焦虑率、抑郁率均高于无IBS组,两组比较差异有统计学意义(P＜0.05).④PDS组(53例)重叠便秘型IBS占33.9％,腹泻型IBS占1.9％,无一例混合型和未定型患者,无IBS率为64.2％；EPS组(67例)重叠便秘型IBS占7.5％,腹泻型IBS占20.9％,混合型占1.5％,无一例未定型患者,无IBS率为70.1％,PDS组与EPS组合并IBS亚型的构成比不同.结论 FD患者合并焦虑抑郁状态率较高,PDS组和EPS组的焦虑抑郁率比较差异无统计学意义(P＞0.05)；FD重叠IBS者合并焦虑抑郁率高于单纯FD患者；PDS组中重叠便秘型IBS的比例高于EPS组,EPS组重叠腹泻型IBS的比例高于PDS组.
목적 분석공능성소화불량환자(FD)적증상여억욱초필상황적상관관계.방법 안라마Ⅲ표준장120례공능성소화불량환자분위찬후불괄종합정(PDS)화상복동통종합정(EPS)량조,설립대조조,입조자안표준완성초필자평량표(SAS)화억욱자평량표(SDS).통과SPSS 16.0통계연건분석FD환자적초필억욱상태,이급FD분형、중첩장역격종합정(IBS)여억욱초필상황적상호관계.결과 ①FD조합병초필상태솔위63.3％,억욱솔위70％；대조조합병초필상태솔위19.2％,억욱솔위7.5％,FD조고우대조조,차이유통계학의의(P＜0.05).②PDS조합병초필、억욱상태솔분별시69.8％、73.6％,EPS합병초필、억욱상태솔위58.2％、67.2％,량조비교차이무통계학의의(P＞0.05).③장소유환자분위무IBS조(81례)여중첩IBS조(39례),무IBS조무초필자점51.9％,합병초필솔자점48.1％；무억욱솔위37.0％,합병억욱솔위63.0％.중첩IBS조무초필자점5.1％,합병초필자점94.9％；무억욱솔위15.4％,합병억욱솔위84.6％.중첩IBS조합병초필솔、억욱솔균고우무IBS조,량조비교차이유통계학의의(P＜0.05).④PDS조(53례)중첩편비형IBS점33.9％,복사형IBS점1.9％,무일례혼합형화미정형환자,무IBS솔위64.2％；EPS조(67례)중첩편비형IBS점7.5％,복사형IBS점20.9％,혼합형점1.5％,무일례미정형환자,무IBS솔위70.1％,PDS조여EPS조합병IBS아형적구성비불동.결론 FD환자합병초필억욱상태솔교고,PDS조화EPS조적초필억욱솔비교차이무통계학의의(P＞0.05)；FD중첩IBS자합병초필억욱솔고우단순FD환자；PDS조중중첩편비형IBS적비례고우EPS조,EPS조중첩복사형IBS적비례고우PDS조.
Objective To analyze the realationship of anxiety and depression states in the patients with functional dyspepsia.Methods The patients with functional dyspepsia(FD) were divided into two groups which included postprandial distress syndrome (PDS) and epigastria pain syndrome(EPS).Set control group.All the candidates had finished the self rating scale in anxiety and depression.The relationship between the FD patients' state of depression and anxiety and Roma Ⅲ subtypes,overlapping irritable bowel syndrome(IBS) was analyzed by SPSS 16.0.Results ①The ratios of anxiety and depression state in the FD patients (63.3％,70％) were higher than that of control group (19.2％,7.5％).②The ratios of anxiety and depression state in the PDS were 69.8％ and 73.6％,and those in the EPS were 58.2％ and 67.2％.There was no significantly different between the two groups.③In the FD group no overlapping IBS,the ratios of no accompanied by anxiety and depression were 51.9％ and 37.0％,and the ratios of accompanied by anxiety and depression were 48.1％ and 63.0％.In the group of FD overlapping IBS,the ratios of no accompanied by anxiety and depression were 5.1％ and 15.4％,and the ratios of accompanied by anxiety and depression were 94.9％ and 84.6％.There were significant differences in the ratios of anxiety and depression state between FD overlapping IBS and its counterpart no overlapping IBS.④The ratios of IBS-constipation,IBS-diarrhea,IBS-mix,non IBS in the PDS were 33.9％,1.9％,0,64.2％and those in the EPS were 7.5％,20.9％,1.5％,70.1％.It was significantly different between the PDS and the EPS.Conclusions The ratios of anxiety and depression state in the FD patients were higher than that of control group.The patients with FD overlapping IBS were accompanied by anxiety and depression state more commonly than the counterpart not overlapping IBS.The ratio of IBS-constipation in the PDS was higher than that in the EPS and the ratio of IBS-diarrhea in the EPS was higher than that in the PDS