CAJ | 학술논문

目的观察帕瑞昔布钠联合静脉自控镇痛(PCA)在腔镜甲状腺术后的镇痛效果.方法将在气管插管全身麻醉下接受腔镜甲状腺大部分切除术的48例患者随机分为两组:观察组26例患者术毕静脉注射帕瑞昔布钠40 mg后连接PCA泵,12h后追加帕瑞昔布钠40 mg,而对照组22例在术毕仅连接PCA泵.于术后4、8、12和24 h时点采用视觉模拟评分法(VAS)进行疼痛评分,同时观测PCA按压次数和用药总量.结果观察组术后4、8、12和24 h时点VAS疼痛评分及PCA按压次数和用药总量均明显低于对照组,差异有统计学意义(P＜0.05).结论帕瑞昔布钠能明显增强腔镜甲状腺术后的镇痛效果,减少PCA的用药量.
목적 관찰파서석포납연합정맥자공진통(PCA)재강경갑상선술후적진통효과.방법 장재기관삽관전신마취하접수강경갑상선대부분절제술적48례환자수궤분위량조:관찰조26례환자술필정맥주사파서석포납40 mg후련접PCA빙,12h후추가파서석포납40 mg,이대조조22례재술필부련접PCA빙.우술후4、8、12화24 h시점채용시각모의평분법(VAS)진행동통평분,동시관측PCA안압차수화용약총량.결과 관찰조술후4、8、12화24 h시점VAS동통평분급PCA안압차수화용약총량균명현저우대조조,차이유통계학의의(P＜0.05).결론 파서석포납능명현증강강경갑상선술후적진통효과,감소PCA적용약량.
Objective To observe the effect of parecoxib sodium combined intravenous patient-controlled analgesia(PCA) in the postoperative analgesia for laparoscopic thyroidectomy.Methods Fortyeight patients who underwent laparoscopic thyroidectomy under tracheal intubation general anesthesia randomly divided into two groups,For the observation group 26 patients injected parecoxib sodium 40 mg then connected with PCA pumps after operations,12 hours after chasing parecoxib sodium 40 mg,while the control group 22 patients just connected with PCA pumps after operations.After 4,8,12 and 24 hour time points using VAS pain scores,while observing the PCA pressing times and medication total.Results Observation group after 4,8,12 and 24 hour time point VAS pain scores and PCA pressing times and medication total were significantly lower than that of control group,the difference was statistically significant (P ＜ 0.05).Conclusions Parecoxib sodium can significantly enhance the analgesic effect of endoscopic thyroid surgery,and reduce the dosage of the PCA.