中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
7期
32-34
,共3页
李怀营%张世昌%王莉萍%袁小锋%李萍%郭会敏
李懷營%張世昌%王莉萍%袁小鋒%李萍%郭會敏
리부영%장세창%왕리평%원소봉%리평%곽회민
新生儿%败血症%降钙素原
新生兒%敗血癥%降鈣素原
신생인%패혈증%강개소원
Neonatal%Septicemia%Procalcitonin
目的 探讨新生儿败血症早期诊断的非特异性指标,为临床早期快速准确诊断提供依据,指导治疗.方法 采用半定量固相免疫法对63例感染患儿的血清进行降钙素原(PCT)检测,同时应用免疫比浊法检测超敏C-反应蛋白(hs-CRP)、血常规并对与感染相关的临床症状进行分析.结果 在新生儿败血症中,PCT的灵敏度最高,相关临床症状中,发热及黄疸是早期诊断败血症的重要线索,为避免早期漏诊提供重要依据.结论 PCT及hs-CRP浓度的检测为早期诊断败血症提供重要依据,结合临床相关因素,可避免漏诊,提高临床诊断率及治愈率.
目的 探討新生兒敗血癥早期診斷的非特異性指標,為臨床早期快速準確診斷提供依據,指導治療.方法 採用半定量固相免疫法對63例感染患兒的血清進行降鈣素原(PCT)檢測,同時應用免疫比濁法檢測超敏C-反應蛋白(hs-CRP)、血常規併對與感染相關的臨床癥狀進行分析.結果 在新生兒敗血癥中,PCT的靈敏度最高,相關臨床癥狀中,髮熱及黃疸是早期診斷敗血癥的重要線索,為避免早期漏診提供重要依據.結論 PCT及hs-CRP濃度的檢測為早期診斷敗血癥提供重要依據,結閤臨床相關因素,可避免漏診,提高臨床診斷率及治愈率.
목적 탐토신생인패혈증조기진단적비특이성지표,위림상조기쾌속준학진단제공의거,지도치료.방법 채용반정량고상면역법대63례감염환인적혈청진행강개소원(PCT)검측,동시응용면역비탁법검측초민C-반응단백(hs-CRP)、혈상규병대여감염상관적림상증상진행분석.결과 재신생인패혈증중,PCT적령민도최고,상관림상증상중,발열급황달시조기진단패혈증적중요선색,위피면조기루진제공중요의거.결론 PCT급hs-CRP농도적검측위조기진단패혈증제공중요의거,결합림상상관인소,가피면루진,제고림상진단솔급치유솔.
Objective To investigate the non-specific indicator of early neonatal septicemia,and to provide early quickly accurate diagnostic evidence for the clinic and direct treatment.Methods Sixty-three serum samples of neonatal infection were measured for PCT by semiquantitative solid-phase immunochromatography and hs-CRP by immunoturbidi-metry assay and tested for comparison white blood cell count(WBC).And the clinical symptoms correlated with infection were analyzed.Results PCT was a better diagnostic marker with higher sensitivity compared with high-sensitive C-reactive protein.Fever and jaundice were important diagnostic clues in clinical symptoms correlated with early neonatal septicemia.Important basis was provided for avoiding early missed diagnosis.Conclusions The concentration dentection of PCT and hs-CRP may provide important diagnostic evidence for early neonatal septicemia.Clinical relevant factors united may avoid missed diagnosis and enhance diagnostic rate and cure rate.