中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
7期
63-64
,共2页
腹腔镜%甲氨蝶呤%米非司酮%异位妊娠
腹腔鏡%甲氨蝶呤%米非司酮%異位妊娠
복강경%갑안접령%미비사동%이위임신
Laparoscope%Methotrexate%Mifepristone%Ectopic pregnancy
目的 探讨术前肌肉注射甲氨蝶呤(MTX)及口服米非司酮联合腹腔镜保守性手术治疗未破裂异位妊娠的临床价值.方法 回顾性分析2011年1月至2012年4月收治于郑州大学第一附属医院的生育期女性要求保留生育功能的40例异位妊娠患者的临床资料,分为治疗组和对照组,每组20例,治疗组给予术前应用MTX及米非司酮联合腹腔镜保守性手术,对照组给予单纯腹腔镜保守性手术,对比分析两组的术中出血量、手术时间、术后第4天血人绒毛膜促性腺激素(HCG)下降率、术后宫内妊娠率.结果 与对照组相比,治疗组的术中出血量和手术时间均显著降低,术后第4天血人绒毛膜促性腺激素(HCG)下降率和术后宫内妊娠率显著提高,两组比较差异有统计学意义(P＜0.05).结论 术前应用MTX及米非司酮联合腹腔镜保守性手术治疗未破裂型异位妊娠疗效好、恢复快,有重要临床应用价值,可作为术前常规用药.
目的 探討術前肌肉註射甲氨蝶呤(MTX)及口服米非司酮聯閤腹腔鏡保守性手術治療未破裂異位妊娠的臨床價值.方法 迴顧性分析2011年1月至2012年4月收治于鄭州大學第一附屬醫院的生育期女性要求保留生育功能的40例異位妊娠患者的臨床資料,分為治療組和對照組,每組20例,治療組給予術前應用MTX及米非司酮聯閤腹腔鏡保守性手術,對照組給予單純腹腔鏡保守性手術,對比分析兩組的術中齣血量、手術時間、術後第4天血人絨毛膜促性腺激素(HCG)下降率、術後宮內妊娠率.結果 與對照組相比,治療組的術中齣血量和手術時間均顯著降低,術後第4天血人絨毛膜促性腺激素(HCG)下降率和術後宮內妊娠率顯著提高,兩組比較差異有統計學意義(P＜0.05).結論 術前應用MTX及米非司酮聯閤腹腔鏡保守性手術治療未破裂型異位妊娠療效好、恢複快,有重要臨床應用價值,可作為術前常規用藥.
목적 탐토술전기육주사갑안접령(MTX)급구복미비사동연합복강경보수성수술치료미파렬이위임신적림상개치.방법 회고성분석2011년1월지2012년4월수치우정주대학제일부속의원적생육기녀성요구보류생육공능적40례이위임신환자적림상자료,분위치료조화대조조,매조20례,치료조급여술전응용MTX급미비사동연합복강경보수성수술,대조조급여단순복강경보수성수술,대비분석량조적술중출혈량、수술시간、술후제4천혈인융모막촉성선격소(HCG)하강솔、술후궁내임신솔.결과 여대조조상비,치료조적술중출혈량화수술시간균현저강저,술후제4천혈인융모막촉성선격소(HCG)하강솔화술후궁내임신솔현저제고,량조비교차이유통계학의의(P＜0.05).결론 술전응용MTX급미비사동연합복강경보수성수술치료미파렬형이위임신료효호、회복쾌,유중요림상응용개치,가작위술전상규용약.
Objective To investigate the clinical value of preoperative intramuscular injection of methotrexate(MTX) and oral taken of mifepristone combined with laparoscopic conservative surgery on unruptured ectopic pregnancy.Methods The clinical data of 40 ectopic pregnancy cases who require reproductive function treated in the first affiliated hospital of Zhengzhou university from 2011 January.to 2012 April were retrospectively analzed.And they were divided into the therapeutic group(20 cases) and control group(20 cases).The patients in the therapeutic group were treated with preoperative application of MTX and mifepristone combined with laparoscopic conservative surgery,the patients in control group were treated with laparoscopic conservative surgery only.The amount of intraoperative bleeding,operation time,decreasing rate of serum human chorionic gonadotropin(HCG) at the postoperative fourth day and incidence of postoperative intrauterine pregnancy in the two groups were compared.Results Compared with the control group,the amount of intraoperative bleeding and operation time in the therapeutic group decreased significantly,decreasing rate of serum HCG at the postoperative fourth day and incidence of postoperative intrauterine pregnancy increased significantly,the difference was significant(P ＜ 0.05).Conclusions Preoperative application of MTX and mifepristone combined with laparoscopic conservative operation in the treatment of unruptured ectopic pregnancy showed good curative effect and quick recovery,and it had important clinical value.It can be used as a routine preoperative medication.
