中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
20期
19-20
,共2页
瑞舒伐他汀钙%不稳定型心绞痛%血脂%C-反应蛋白
瑞舒伐他汀鈣%不穩定型心絞痛%血脂%C-反應蛋白
서서벌타정개%불은정형심교통%혈지%C-반응단백
Rosuvastatin calcium%Unstable angina%Lipids%C-reactive protein
目的 探讨瑞舒伐他汀钙对不稳定型心绞痛患者血脂及炎症因子C-反应蛋白的影响.方法 将70例患者随机分为治疗组和对照组,每组35例,对照组以硝酸酯类、β-受体阻滞剂、血管紧张素转换酶抑制剂、抗血小板作为常规治疗,治疗组在常规治疗基础上给予瑞舒伐他汀钙治疗,比较两组用药前后C-反应蛋白水平及血脂变化.结果 两组治疗后C-反应蛋白及血脂水平均较前降低,治疗组下降明显优于对照组,两组比较差异有统计学意义(P＜0.05).结论 瑞舒伐他汀钙治疗不稳定型心绞痛不但能降低血脂,还可减轻其炎性反应,稳定动脉粥样斑块.
目的 探討瑞舒伐他汀鈣對不穩定型心絞痛患者血脂及炎癥因子C-反應蛋白的影響.方法 將70例患者隨機分為治療組和對照組,每組35例,對照組以硝痠酯類、β-受體阻滯劑、血管緊張素轉換酶抑製劑、抗血小闆作為常規治療,治療組在常規治療基礎上給予瑞舒伐他汀鈣治療,比較兩組用藥前後C-反應蛋白水平及血脂變化.結果 兩組治療後C-反應蛋白及血脂水平均較前降低,治療組下降明顯優于對照組,兩組比較差異有統計學意義(P＜0.05).結論 瑞舒伐他汀鈣治療不穩定型心絞痛不但能降低血脂,還可減輕其炎性反應,穩定動脈粥樣斑塊.
목적 탐토서서벌타정개대불은정형심교통환자혈지급염증인자C-반응단백적영향.방법 장70례환자수궤분위치료조화대조조,매조35례,대조조이초산지류、β-수체조체제、혈관긴장소전환매억제제、항혈소판작위상규치료,치료조재상규치료기출상급여서서벌타정개치료,비교량조용약전후C-반응단백수평급혈지변화.결과 량조치료후C-반응단백급혈지수평균교전강저,치료조하강명현우우대조조,량조비교차이유통계학의의(P＜0.05).결론 서서벌타정개치료불은정형심교통불단능강저혈지,환가감경기염성반응,은정동맥죽양반괴.
Objective To investigate the effect of rosuvastatin calcium on lipids and inflammatory factors C-reactive protein in patients with unstable angina.Methods Totally seventy patients with unstable angina were chosen in the study.The patients were randomly divided into two groups:the control group (n =35) and the therapeutic group(n =35).The patients in control group were treated by routine therapy with nitrates,β-blockers,ACEI and antibloodplatelet therapy.The patients in therapeutic group were treated with rosuvastatin calcium on the basis of routine therapy.The levels of C-reactive protein and lipids were measured before and after treatment in both groups.Results After treatment,the level of Creactive protein and lipids decreased.And the therapeutic group decreased more than the control group,the difference was statistically significant (P ＜ 0.05).Conclusions Rosuvastatin calcium in treatment of unstable angina can not only reduce cholesterol,but also reduce the inflammatory response,so it is conducive to atherosclerosis plaque stability.
