CAJ | 학술논문

目的调查滨州市人民医院重症监护室的感染细菌分布及其耐药性变化状况,为有效控制感染、合理应用抗菌药物提供参考依据.方法搜集滨州市人民医院2011年11月至2012年10月间重症监护室(ICU)送检的标本进行统计分析.结果 2011年11月至2012年10月间ICU共培养阳性病例388例,院内感染分离率为40.26％,分离菌株中鲍曼不动杆菌比例最高,为32.99％；其次为肺炎克雷伯杆菌和铜绿假单胞菌,构成比分别为17.78％和17.53％.对鲍曼不动杆菌的抗菌药物中头孢哌酮钠舒巴坦钠的耐药率为27.8％,米诺环素的耐药率为34.6％,美罗培南、亚胺培南的耐药率均达到90％以上.结论鲍曼不动杆菌是ICU感染的主要菌株,及时送检及根据药敏试验结果选用抗菌药物是院内感染控制的关键,可有效避免和延缓耐药菌株的发生和扩大.
목적 조사빈주시인민의원중증감호실적감염세균분포급기내약성변화상황,위유효공제감염、합리응용항균약물제공삼고의거.방법 수집빈주시인민의원2011년11월지2012년10월간중증감호실(ICU)송검적표본진행통계분석.결과 2011년11월지2012년10월간ICU공배양양성병례388례,원내감염분리솔위40.26％,분리균주중포만불동간균비례최고,위32.99％；기차위폐염극뢰백간균화동록가단포균,구성비분별위17.78％화17.53％.대포만불동간균적항균약물중두포고동납서파탄납적내약솔위27.8％,미낙배소적내약솔위34.6％,미라배남、아알배남적내약솔균체도90％이상.결론 포만불동간균시ICU감염적주요균주,급시송검급근거약민시험결과선용항균약물시원내감염공제적관건,가유효피면화연완내약균주적발생화확대.
Objective To observe the bacterial infection distribution and drug resistance in ICU of Binzhou people's hospital,in order to provide the rational using of antibacterial drugs.Methods The species distribution and drug resistance of bacteria isolated from November 2011 to October 2012 in Binzhou people' s hospital were analyzed.Results Among the ICU patients,bacteria separation acounted for 40.26％,including 128 cases of Acinetobacter baumannii,accounting for 32.99％.Klebsiella pneumoniae and Pseudomonas aeruginosa accounted for 17.78％ and 17.53％.The rsistance rates of Acinetobacter to Cefoperazone,Minocycline,Meropenem,Imipenem were 27.8％,34.6％,94.4％,95.1％.Conclusions Acinetobacter baumannii is the main infectious pathogen in ICU.Early diagnosis and rational use of antibacterial drugs are the key to prevention and treatment of hospital infection.The occurrence and expand of resistant strains and expand should be avoid and delayed.