中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
23期
101-103
,共3页
帕瑞昔布钠%地佐辛%开胸手术%麻醉恢复期
帕瑞昔佈鈉%地佐辛%開胸手術%痳醉恢複期
파서석포납%지좌신%개흉수술%마취회복기
Parecoxib sodium%Dezocine%Thoracotomy%Anesthesia recovery period
目的 探讨帕瑞昔布钠复合地佐辛对提高开胸术患者麻醉恢复期质量的效果.方法 择期开胸手术患者60例,随机分为三组(n=20):P组:麻醉前10 min静脉注射帕瑞昔布钠40 mg(5 ml);D组:术毕前20 min静脉注射地佐辛0.2 mg/kg; PD组:麻醉前10 min静脉注射帕瑞昔布钠40 mg(5 ml)+术毕前20 min静脉注射地佐辛0.1 mg/kg.于麻醉前(T1)、拔管前即刻(T2)、拔管后l min(T3)、拔管后5 min (T4)时记录呼吸(HR)、平均动脉压(MAP),记录苏醒、拔管时间.评估拔管后5 min时的躁动(RS)评分、镇静(RSS)评分,和舒适(BCS)评分.结果 与PD组相比,P组T2、T3时刻HR增快,MAP增高;RS评分增高,与D组、PD相比差异有统计学意义(P＜0.05);D组苏醒、拔管时间延长,RSS评分增高,与P组、PD相比差异有统计学意义(P ＜0.05);PD组BCS评分增高,与P组、D相比差异有统计学意义(P＜0.05).结论 麻醉前10 min帕瑞昔布钠40 mg复合术毕前20 min0.1 mg/kg地佐辛静注用于开胸手术后,患者有满意的麻醉恢复期循环变化,且不影响患者的苏醒、拔管时间,苏醒质量高,具有一定的临床应用价值.
目的 探討帕瑞昔佈鈉複閤地佐辛對提高開胸術患者痳醉恢複期質量的效果.方法 擇期開胸手術患者60例,隨機分為三組(n=20):P組:痳醉前10 min靜脈註射帕瑞昔佈鈉40 mg(5 ml);D組:術畢前20 min靜脈註射地佐辛0.2 mg/kg; PD組:痳醉前10 min靜脈註射帕瑞昔佈鈉40 mg(5 ml)+術畢前20 min靜脈註射地佐辛0.1 mg/kg.于痳醉前(T1)、拔管前即刻(T2)、拔管後l min(T3)、拔管後5 min (T4)時記錄呼吸(HR)、平均動脈壓(MAP),記錄囌醒、拔管時間.評估拔管後5 min時的躁動(RS)評分、鎮靜(RSS)評分,和舒適(BCS)評分.結果 與PD組相比,P組T2、T3時刻HR增快,MAP增高;RS評分增高,與D組、PD相比差異有統計學意義(P＜0.05);D組囌醒、拔管時間延長,RSS評分增高,與P組、PD相比差異有統計學意義(P ＜0.05);PD組BCS評分增高,與P組、D相比差異有統計學意義(P＜0.05).結論 痳醉前10 min帕瑞昔佈鈉40 mg複閤術畢前20 min0.1 mg/kg地佐辛靜註用于開胸手術後,患者有滿意的痳醉恢複期循環變化,且不影響患者的囌醒、拔管時間,囌醒質量高,具有一定的臨床應用價值.
목적 탐토파서석포납복합지좌신대제고개흉술환자마취회복기질량적효과.방법 택기개흉수술환자60례,수궤분위삼조(n=20):P조:마취전10 min정맥주사파서석포납40 mg(5 ml);D조:술필전20 min정맥주사지좌신0.2 mg/kg; PD조:마취전10 min정맥주사파서석포납40 mg(5 ml)+술필전20 min정맥주사지좌신0.1 mg/kg.우마취전(T1)、발관전즉각(T2)、발관후l min(T3)、발관후5 min (T4)시기록호흡(HR)、평균동맥압(MAP),기록소성、발관시간.평고발관후5 min시적조동(RS)평분、진정(RSS)평분,화서괄(BCS)평분.결과 여PD조상비,P조T2、T3시각HR증쾌,MAP증고;RS평분증고,여D조、PD상비차이유통계학의의(P＜0.05);D조소성、발관시간연장,RSS평분증고,여P조、PD상비차이유통계학의의(P ＜0.05);PD조BCS평분증고,여P조、D상비차이유통계학의의(P＜0.05).결론 마취전10 min파서석포납40 mg복합술필전20 min0.1 mg/kg지좌신정주용우개흉수술후,환자유만의적마취회복기순배변화,차불영향환자적소성、발관시간,소성질량고,구유일정적림상응용개치.
Objective To investigate the effectivness of parecoxib sodium combined with dezocine on improvement of the quality in the anesthesia recovery period after thoracotomy.Methods Sixty patients received thoracotomy under elective general anesthesia were randomly divided into three groups:group P(n =20):parecoxib sodium 40 mg intravenously 10 min before anesthesia,group D(n =20):dezocine 0.2 mg/kg intravenously 20 min before the end of surgery,group PD (n =20):parecoxib sodium 40 mg intravenously 10 min before anesthesia combined with dezocine 0.1 mg/kg intravenously 20 min before the end of surgery.The HR and MAP were recorded before anesthesia(T1),before extubation (T2),after extubation 1 min(T3),5 min(T4).The time of analepsia and extubation were recorded.The RS,RSS and BCS scores were also recorded.Results The group P were higher than group D and group PD in the changes of HR,MAP and the RS score,the difference was statistically significant(P ＜0.05).The group D were higher than group P and group PD in the length time of analepsia,extubation and the RSS score,the difference was statistically significant(P ＜ 0.05).The group PD were higher than group D and group P in the BCS score,the difference was statistically significant (P ＜ 0.05).Conclusions Parecoxib sodium 40 mg intravenously 10 min before sugery combined with dezocine 0.1 mg/kg intravenously 20 min before the end of surgery was a good choice in the anesthesia recovery period after thoracotomy,without affecting the time of analepsia and extubation,with satisfactory circulation changes and high quality of analepsia.
