中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
24期
14-15
,共2页
参苓白术散%慢性肾小球肾炎%T淋巴细胞亚群%免疫球蛋白
參苓白術散%慢性腎小毬腎炎%T淋巴細胞亞群%免疫毬蛋白
삼령백술산%만성신소구신염%T림파세포아군%면역구단백
Shenlingbaizhu powder%Chronic glomerulonephritis%T lymphocyte subsets%Immunoglobulin
目的 观察参苓白术散对慢性肾小球肾炎患者T淋巴细胞亚群CD3+、CD4+、CD4+/CD8+,免疫球蛋白IgA、IgG、IgM等免疫指标的影响.方法 将65例慢性肾小球肾炎患者随机分为观察组33例和对照组32例,对照组采用常规治疗,观察组在常规治疗的基础上加用参苓白术散.观察两组患者治疗前后血清CD3+、CD4+、CD4 +/CD8+,免疫球蛋白IgA、IgG、IgM变化情况及临床症状缓解情况.结果 观察组治疗后较对照组CD3+、CD4+、CD4+/CD8+水平及免疫球蛋白IgA、IgG水平有效升高,且观察组疗效优于对照组,差异均有统计学意义(P＜0.05).结论 参苓白术散可提高慢性肾小球肾炎患者的免疫功能,减轻肾组织损伤,改善临床症状.
目的 觀察參苓白術散對慢性腎小毬腎炎患者T淋巴細胞亞群CD3+、CD4+、CD4+/CD8+,免疫毬蛋白IgA、IgG、IgM等免疫指標的影響.方法 將65例慢性腎小毬腎炎患者隨機分為觀察組33例和對照組32例,對照組採用常規治療,觀察組在常規治療的基礎上加用參苓白術散.觀察兩組患者治療前後血清CD3+、CD4+、CD4 +/CD8+,免疫毬蛋白IgA、IgG、IgM變化情況及臨床癥狀緩解情況.結果 觀察組治療後較對照組CD3+、CD4+、CD4+/CD8+水平及免疫毬蛋白IgA、IgG水平有效升高,且觀察組療效優于對照組,差異均有統計學意義(P＜0.05).結論 參苓白術散可提高慢性腎小毬腎炎患者的免疫功能,減輕腎組織損傷,改善臨床癥狀.
목적 관찰삼령백술산대만성신소구신염환자T림파세포아군CD3+、CD4+、CD4+/CD8+,면역구단백IgA、IgG、IgM등면역지표적영향.방법 장65례만성신소구신염환자수궤분위관찰조33례화대조조32례,대조조채용상규치료,관찰조재상규치료적기출상가용삼령백술산.관찰량조환자치료전후혈청CD3+、CD4+、CD4 +/CD8+,면역구단백IgA、IgG、IgM변화정황급림상증상완해정황.결과 관찰조치료후교대조조CD3+、CD4+、CD4+/CD8+수평급면역구단백IgA、IgG수평유효승고,차관찰조료효우우대조조,차이균유통계학의의(P＜0.05).결론 삼령백술산가제고만성신소구신염환자적면역공능,감경신조직손상,개선림상증상.
Objective To observe the effect of Shenlingbaizhu powder on lymphocyte T subtype CD3 +,CD4 +,CD4 +/CD8 +,immunoglobulin IgA,IgG,IgM and immune parameters in patients with chronic glomerular nephritis.Methods Sixty-five patients with chronic glomerular nephritis were randomly divided into observation group (33 cases) and control group (32 cases),patients in control group were given the routine treatment,and patients in observation group were given Shenlingbaizhu powder on the basis of routine treatment.The serum CD3 +,CD4 +,CD4 +/CD8 +,immunoglobulin IgA,IgG,IgM changes and clinical symptoms in both groups before and after treatment were observed.Results Compared with the control group,the levels of CD3+,CD4+,CD4+/CD8+ (P ＜0.05) and immunoglobulin IgA,IgG increased in observation group (P ＜ 0.05) after treatment,and the clinical curative effect of observation group was better than that of control group.There were statistically significant differences between the two groups (P ＜ 0.05).Conclusions Shenlingbaizhu powder can improve the immune function in patients with chronic glomerulonephritis,reduce the renal tissue damage,and improve the clinical symptoms.
