CAJ | 학술논문

目的研究在放大内镜下应用窄带成像(NBI)技术观察幽门螺杆菌(Hp)感染时胃体黏膜微细结构变化的特征,进而探讨NBI在判断Hp相关性胃炎中的作用.方法在放大内镜下应用NBI对180例有不同上消化道症状患者的胃体黏膜微细结构进行观察和分型,用胃黏膜组织学检查(生物电荷法)和13C呼气试验检测Hp感染,分析胃体黏膜微细结构与Hp之间的联系.结果 180例患者中Hp感染阳性72例,Hp感染阴性108例,胃体下部大弯侧集合静脉分为规则型(R)、不规则型(Ⅰ)、消失型(D),Hp感染率分别为6.5％、65.2％和81.5％,其中D及Ⅰ型感染率明显高于R型,且差异有统计学意义(P＜0.05).结论在放大内镜及NBI下Hp感染时胃体黏膜微细结构特点是集合静脉不规则、紊乱、模糊、甚至消失,且图像清晰度显著优于单独应用放大内镜.
목적 연구재방대내경하응용착대성상(NBI)기술관찰유문라간균(Hp)감염시위체점막미세결구변화적특정,진이탐토NBI재판단Hp상관성위염중적작용.방법 재방대내경하응용NBI대180례유불동상소화도증상환자적위체점막미세결구진행관찰화분형,용위점막조직학검사(생물전하법)화13C호기시험검측Hp감염,분석위체점막미세결구여Hp지간적련계.결과 180례환자중Hp감염양성72례,Hp감염음성108례,위체하부대만측집합정맥분위규칙형(R)、불규칙형(Ⅰ)、소실형(D),Hp감염솔분별위6.5％、65.2％화81.5％,기중D급Ⅰ형감염솔명현고우R형,차차이유통계학의의(P＜0.05).결론 재방대내경급NBI하Hp감염시위체점막미세결구특점시집합정맥불규칙、문란、모호、심지소실,차도상청석도현저우우단독응용방대내경.
Objective To study the microstructural features of gastric mucosa infecting with He licobacter pylori (Hp) by magnifying endoscopy with narrow-band imaging(NBI),then to study the effect NBI on Hp assciated gastritis.Methods Microstructures of gastric mucosa in 180 patients with dyspepsia were observed and classified by magnifying endoscopy with narrow-band imaging.Biological charge method and the breath test of 13C were used to detect the Hp infection.The relationship between microstructures of gastric mucosa and Hp infection was analyzed.Results Of the 180 patients,Hppositive in 72 cases,and negative in 108 cases.The morphology of lower and greater curvature part of gastric corpus collecting venules was subdivided into type R(regular),type Ⅰ(irregular) and type D(disappeared),correspondent Hp infection rates were 6.5％,65.2％ and 81.5％.The rate of Hp infection in type D and type Ⅰ was significantly higher than that in type R (P ＜ 0.05).Conclusions Under magnifying endoscopy with narrow-band imaging,Hp positive gastric mucosal microstructure shows the features of irregular,confused,obscured or disappeared collecting venules in corpus.The image clarity is significantly better than that of single application of magnifying endoscopy.