中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2013年
24期
75-77
,共3页
慢性肺源性心脏病%中药%超敏C-反应蛋白%N-末端脑钠肽前体
慢性肺源性心髒病%中藥%超敏C-反應蛋白%N-末耑腦鈉肽前體
만성폐원성심장병%중약%초민C-반응단백%N-말단뇌납태전체
Chronec pulmonary heart disease%Traditional Chinese medicine%High sensitive C-reactive protein (hs-CRP)%N-terminal pro-brain natriuretic peptide (NT-proBNP)
目的 探讨化瘀祛痰中药对慢性肺源性心脏病(肺心病)急性期患者血浆超敏C-反应蛋白(hs-CRP)和N-末端脑钠肽前体(NT-proBNP)的影响.方法 将88例肺心病急性期患者随机分为两组,每组44例,对照组采用常规治疗,观察组在常规治疗的基础上加用化瘀祛痰中药;两组共治疗14 d.治疗前后测定患者血浆hs-CRP和NT-proBNP水平.结果 两组治疗后患者平均肺动脉压力(MPAP)均有明显下降(P＜0.01),与对照组比较,观察组治疗后MPAP下降更明显(P＜0.05).两组在治疗后患者的血浆hs-CRP和NT-proBNP均可明显降低,并且观察组降低程度更加明显(P＜0.05).结论 化瘀祛痰中药可以明显减轻肺心病急性期患者的炎症状态,从而改善右心功能.
目的 探討化瘀祛痰中藥對慢性肺源性心髒病(肺心病)急性期患者血漿超敏C-反應蛋白(hs-CRP)和N-末耑腦鈉肽前體(NT-proBNP)的影響.方法 將88例肺心病急性期患者隨機分為兩組,每組44例,對照組採用常規治療,觀察組在常規治療的基礎上加用化瘀祛痰中藥;兩組共治療14 d.治療前後測定患者血漿hs-CRP和NT-proBNP水平.結果 兩組治療後患者平均肺動脈壓力(MPAP)均有明顯下降(P＜0.01),與對照組比較,觀察組治療後MPAP下降更明顯(P＜0.05).兩組在治療後患者的血漿hs-CRP和NT-proBNP均可明顯降低,併且觀察組降低程度更加明顯(P＜0.05).結論 化瘀祛痰中藥可以明顯減輕肺心病急性期患者的炎癥狀態,從而改善右心功能.
목적 탐토화어거담중약대만성폐원성심장병(폐심병)급성기환자혈장초민C-반응단백(hs-CRP)화N-말단뇌납태전체(NT-proBNP)적영향.방법 장88례폐심병급성기환자수궤분위량조,매조44례,대조조채용상규치료,관찰조재상규치료적기출상가용화어거담중약;량조공치료14 d.치료전후측정환자혈장hs-CRP화NT-proBNP수평.결과 량조치료후환자평균폐동맥압력(MPAP)균유명현하강(P＜0.01),여대조조비교,관찰조치료후MPAP하강경명현(P＜0.05).량조재치료후환자적혈장hs-CRP화NT-proBNP균가명현강저,병차관찰조강저정도경가명현(P＜0.05).결론 화어거담중약가이명현감경폐심병급성기환자적염증상태,종이개선우심공능.
Objective To study the effect of stasis expectorant traditional chinese medicine on serum levels of high-sensitive C-reactive protein (hs-CRP) and N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients with chronic pulmonary heart disease in acute period.Methods Eighty-eight patients with pulmonary heart disease in acute period were randomly divided into two groups,the observation group (44 cases) and the control group (44 cases).The patients in the control group were treated with conventional treatment,while the patients in the observation group were treated with the conventional tretment and stasis expectorant traditional chinese medicine.They were all treated for 14 days.Serum hsCRP and NT-proBNP levels were detected before and after treatment.Results The mean pulmonary arterial pressure(MPAP) decreased obviously after treatment in both groups(P ＜ 0.01).Compared with the control group,MPAP drceased more obviously after treatment in observation group (P ＜ 0.05).Serum hs-CRP and NT-proBNP levels decreased obviously after treatment in both group,and serum hs-CRP and NT-proBNP levels in the observation group were lower than those in the control group (P ＜ 0.05).Conclusions Stasis expectorant traditional chinese medicine can decrease inflammatory state of patients with pulmonary heart disease in acate period,which can improve the right heart function.
