中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2014年
3期
22-23
,共2页
肠球菌属%耐药性%抗菌素
腸毬菌屬%耐藥性%抗菌素
장구균속%내약성%항균소
Enterococcus%Drug resistance%Antibacterials
目的 了解肠球菌属细菌在临床标本中的分布及对常用抗菌药物的耐药性,指导临床合理选择抗菌药物.方法 对2011年1月至2012年12月各临床标本中分离的368肠球菌属的细菌菌种分布及药敏结果进行回顾性分析.结果 368株肠球菌属细菌中屎肠球菌213株,占58.0％;粪肠球菌145株,占39.3％;鹑鸡肠球菌4株,占1.1％;铅黄肠球菌3株,占0.8％;耐久肠球菌3株,占0.8％.肠球菌属细菌主要分离自尿液、血液、切口分泌物中,检出率分别为53.0％、13.6％、12.2％.粪肠球菌对红霉素、环丙沙星、喹奴普汀/达福普汀和利福平的耐药性较高,耐药率均＞60％,而对青霉素、氨苄西林的耐药率则＜20％;屎肠球菌对青霉素、氨苄西林、红霉素、环丙沙星、利福平、左氧氟沙星的耐药率均＞95％,而对喹奴普汀/达福普汀和四环素耐药率较低,分别为11.3％和35.6％;两种肠球菌对万古霉素、替考拉宁、利奈唑胺的耐药率均＜2％.结论 肠球菌属细菌对抗茵药物的耐药性较高,而且屎肠球菌和粪肠球菌的耐药性明显不同,临床治疗时应根据菌株类别和药敏结果合理用药,尽量减少耐药菌株的产生.
目的 瞭解腸毬菌屬細菌在臨床標本中的分佈及對常用抗菌藥物的耐藥性,指導臨床閤理選擇抗菌藥物.方法 對2011年1月至2012年12月各臨床標本中分離的368腸毬菌屬的細菌菌種分佈及藥敏結果進行迴顧性分析.結果 368株腸毬菌屬細菌中屎腸毬菌213株,佔58.0％;糞腸毬菌145株,佔39.3％;鶉鷄腸毬菌4株,佔1.1％;鉛黃腸毬菌3株,佔0.8％;耐久腸毬菌3株,佔0.8％.腸毬菌屬細菌主要分離自尿液、血液、切口分泌物中,檢齣率分彆為53.0％、13.6％、12.2％.糞腸毬菌對紅黴素、環丙沙星、喹奴普汀/達福普汀和利福平的耐藥性較高,耐藥率均＞60％,而對青黴素、氨芐西林的耐藥率則＜20％;屎腸毬菌對青黴素、氨芐西林、紅黴素、環丙沙星、利福平、左氧氟沙星的耐藥率均＞95％,而對喹奴普汀/達福普汀和四環素耐藥率較低,分彆為11.3％和35.6％;兩種腸毬菌對萬古黴素、替攷拉寧、利奈唑胺的耐藥率均＜2％.結論 腸毬菌屬細菌對抗茵藥物的耐藥性較高,而且屎腸毬菌和糞腸毬菌的耐藥性明顯不同,臨床治療時應根據菌株類彆和藥敏結果閤理用藥,儘量減少耐藥菌株的產生.
목적 료해장구균속세균재림상표본중적분포급대상용항균약물적내약성,지도림상합리선택항균약물.방법 대2011년1월지2012년12월각림상표본중분리적368장구균속적세균균충분포급약민결과진행회고성분석.결과 368주장구균속세균중시장구균213주,점58.0％;분장구균145주,점39.3％;순계장구균4주,점1.1％;연황장구균3주,점0.8％;내구장구균3주,점0.8％.장구균속세균주요분리자뇨액、혈액、절구분비물중,검출솔분별위53.0％、13.6％、12.2％.분장구균대홍매소、배병사성、규노보정/체복보정화리복평적내약성교고,내약솔균＞60％,이대청매소、안변서림적내약솔칙＜20％;시장구균대청매소、안변서림、홍매소、배병사성、리복평、좌양불사성적내약솔균＞95％,이대규노보정/체복보정화사배소내약솔교저,분별위11.3％화35.6％;량충장구균대만고매소、체고랍저、리내서알적내약솔균＜2％.결론 장구균속세균대항인약물적내약성교고,이차시장구균화분장구균적내약성명현불동,림상치료시응근거균주유별화약민결과합리용약,진량감소내약균주적산생.
Objective To investigate the distribution of Enterococcus in clinical specimens and their drug resistance to commonly used antibiotics,in order to guide the reasonable selection of antibiotics in clinics.Methods Retrospective analysis was performed with the bacterial distribution and antimicrobial susceptibility results of 368 strains of Enterococcus which were isolated clinically during January 2011 to December 2012.Results Among the 368 strains of Enterococcus,there were 213 strains(58.0％) of Enterococcus faecium,145 strains(39.3％) of Enterococcus faecalis,4 strains(1.1％) of Enterococcus gallimarum,3 strains(0.8％) of Enterococcus casseliflavus,3 strains(0.8％) of Enterococcus durans.The strains were mainly isolated from urine,blood,wound secretion,and the isolation rate was 53.0％,13.6％,12.2％ respectively.Enterococcus faecalis were highly resistant to erythromycin,ciprofloxacin,quinupristin/dalfopristin and rifampin,and the resistance rate was above 60％,and the drug resistant rate of Enterococcus faecalis to penicillin,ampicillin rate was less than 20％ ; the drug resistant rates of Enterococcus faecium resistant to penicillin,ampicillin,erythromycin,ciprofloxacin,levofloxacin,rifampin were higher than 95％,to quinupristin/dalfopristin and tetracycline were 11.3％ and 35.6％,respectively; both of enterococcous resistant to vancomycin,teicoplanin,linezolid rate was less than 2％.Conclusions Enterococcus has highly drug resistance to antibiotics,and Enterococcus faecium and Enterococcus faecalis were different in drug resistance.The clinical treatment should be rational,according to susceptibility test results,in order to minimize the emergence of resistant strains as far as possible.
