中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2014年
3期
34-35
,共2页
进展性脑梗死%炎症因子
進展性腦梗死%炎癥因子
진전성뇌경사%염증인자
Progressive cerebral infarction%Inflammatory factors
目的 对进展性脑梗死患者的血清炎症因子水平的变化情况进行观察分析.方法 选择进展性脑梗死患者、非进展性脑梗死患者及健康人群个体共105例作为研究对象,按患病类型和健康情况将其分为进展性脑梗死组、非进展性脑梗死组和健康人群对照组,每组各35例,对研究对象超敏C-反应蛋白(hs-CRP)、白细胞介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)和血清前白蛋白(PA)进行检测观察.结果 进展性脑梗死组和非进展性脑梗死组患者的hs-CRP、IL-8、TNF-α水平均较对照组显著偏高(P＜0.05),且进展性脑梗死组较非进展性脑梗死组更高(P＜0.05);与对照组比较,进展性脑梗死组和非进展性脑梗死组患者的血清PA水平明显偏低(P＜0.05),且进展性脑死组较非进展性脑梗死组更低(P＜0.05).结论 血清hs-CRP、IL-8、TNF-α、PA等炎症因子水平变化对进展性脑梗死的发病有一定的提示作用.
目的 對進展性腦梗死患者的血清炎癥因子水平的變化情況進行觀察分析.方法 選擇進展性腦梗死患者、非進展性腦梗死患者及健康人群箇體共105例作為研究對象,按患病類型和健康情況將其分為進展性腦梗死組、非進展性腦梗死組和健康人群對照組,每組各35例,對研究對象超敏C-反應蛋白(hs-CRP)、白細胞介素-8(IL-8)、腫瘤壞死因子-α(TNF-α)和血清前白蛋白(PA)進行檢測觀察.結果 進展性腦梗死組和非進展性腦梗死組患者的hs-CRP、IL-8、TNF-α水平均較對照組顯著偏高(P＜0.05),且進展性腦梗死組較非進展性腦梗死組更高(P＜0.05);與對照組比較,進展性腦梗死組和非進展性腦梗死組患者的血清PA水平明顯偏低(P＜0.05),且進展性腦死組較非進展性腦梗死組更低(P＜0.05).結論 血清hs-CRP、IL-8、TNF-α、PA等炎癥因子水平變化對進展性腦梗死的髮病有一定的提示作用.
목적 대진전성뇌경사환자적혈청염증인자수평적변화정황진행관찰분석.방법 선택진전성뇌경사환자、비진전성뇌경사환자급건강인군개체공105례작위연구대상,안환병류형화건강정황장기분위진전성뇌경사조、비진전성뇌경사조화건강인군대조조,매조각35례,대연구대상초민C-반응단백(hs-CRP)、백세포개소-8(IL-8)、종류배사인자-α(TNF-α)화혈청전백단백(PA)진행검측관찰.결과 진전성뇌경사조화비진전성뇌경사조환자적hs-CRP、IL-8、TNF-α수평균교대조조현저편고(P＜0.05),차진전성뇌경사조교비진전성뇌경사조경고(P＜0.05);여대조조비교,진전성뇌경사조화비진전성뇌경사조환자적혈청PA수평명현편저(P＜0.05),차진전성뇌사조교비진전성뇌경사조경저(P＜0.05).결론 혈청hs-CRP、IL-8、TNF-α、PA등염증인자수평변화대진전성뇌경사적발병유일정적제시작용.
Objective To observe and analyze the changes of the levels of inflammatory factors in patients with progressive cerebral infarction.Methods One hundred and five individuals of the patients with progressive cerebral infarction,the patients with non-progressive cerebral infarction and healthy individuals were selected as the research objects.The objects were divided into the progressive cerebral infarction group,the non-progressive cerebral infarction group and the control group according to the disease type and health condition.Thirty-five individuals were included in each group.The levels of high-sensitivity C-reactive protein (hs-CRP),interleukin-8 (IL-8),tumor necrosis factor alpha (TNF-α) and prealbumin (PA) of the research objects were detected and observed.Results The levels of hsCRP,IL-8 and TNF-α of the progressive cerebral infarction group and non-progressive cerebral infarction group were significantly higher than those of the control group (P ＜0.05),and the levels of the progressive cerebral infarction group were significantly higher than those of the non-progressive cerebral infarction group (P ＜ 0.05) ; Compared with the control group,the level of PA of the progressive cerebral infarction group and non-progressive cerebral infarction group were significantly lower (P ＜ 0.05),and the level of the progressive cerebral infarction group was lower than that of the non-progressive cerebral infarction group (P ＜0.05).Conclusions The changes of the inflammatory factors levels such as hs-CRP,IL-8,TNF-α,PA have certain predicative value on the development of the progressive cerebral infarction.
