中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2014年
23期
49-52
,共4页
沙丁胺醇%金水宝胶囊%慢性阻塞性肺疾病%肺功能
沙丁胺醇%金水寶膠囊%慢性阻塞性肺疾病%肺功能
사정알순%금수보효낭%만성조새성폐질병%폐공능
Salbutamol%Jinshuibao capsule%Chronic obstructive pulmonary disease%Lung function
目的 探讨沙丁胺醇联合金水宝胶囊对慢性阻塞性肺疾病患者(COPD)的肺功能、6分钟步行试验(6MWD)和SGRT评分的影响.方法 选择慢性阻塞性肺疾病患者100例,随机分为对照组和观察组,对照组给予沙丁胺醇气雾剂,观察组给予沙丁胺醇和金水宝胶囊.对比治疗后肺功能、6分钟步行距离和SGRT评分等指标变化.结果 两组患者的肺功能、6MWD和SGRT均有所改善.观察组治疗后肺功能指标变化值均大于对照组,在6MWD上高于对照组,SGRT低于对照组,差异均有统计学意义(P＜0.01).经过2周的干预之后,两组第1秒用力呼气容积、第1秒用力呼气容积占预计值百分比,第1秒用力呼气容积/用力肺活量比较,观察组的肺功能指标均好于对照组,差异均有统计学意义(P＜0.05).观察组总有效率为94.00％,对照组为78.00％.经x2检验,观察组疗效明显优于对照组,差异有统计学意义(x2=11.302,P＜0.05).结论 沙丁胺醇联合金水宝胶囊能明显改善稳定期COPD患者肺功能各项指标、提高6分钟步行距离,降低SGRT评分,减少气道阻塞程度,防止支气管痉挛,同时提高自身免疫力,降低西药耐药性及其不良反应.
目的 探討沙丁胺醇聯閤金水寶膠囊對慢性阻塞性肺疾病患者(COPD)的肺功能、6分鐘步行試驗(6MWD)和SGRT評分的影響.方法 選擇慢性阻塞性肺疾病患者100例,隨機分為對照組和觀察組,對照組給予沙丁胺醇氣霧劑,觀察組給予沙丁胺醇和金水寶膠囊.對比治療後肺功能、6分鐘步行距離和SGRT評分等指標變化.結果 兩組患者的肺功能、6MWD和SGRT均有所改善.觀察組治療後肺功能指標變化值均大于對照組,在6MWD上高于對照組,SGRT低于對照組,差異均有統計學意義(P＜0.01).經過2週的榦預之後,兩組第1秒用力呼氣容積、第1秒用力呼氣容積佔預計值百分比,第1秒用力呼氣容積/用力肺活量比較,觀察組的肺功能指標均好于對照組,差異均有統計學意義(P＜0.05).觀察組總有效率為94.00％,對照組為78.00％.經x2檢驗,觀察組療效明顯優于對照組,差異有統計學意義(x2=11.302,P＜0.05).結論 沙丁胺醇聯閤金水寶膠囊能明顯改善穩定期COPD患者肺功能各項指標、提高6分鐘步行距離,降低SGRT評分,減少氣道阻塞程度,防止支氣管痙攣,同時提高自身免疫力,降低西藥耐藥性及其不良反應.
목적 탐토사정알순연합금수보효낭대만성조새성폐질병환자(COPD)적폐공능、6분종보행시험(6MWD)화SGRT평분적영향.방법 선택만성조새성폐질병환자100례,수궤분위대조조화관찰조,대조조급여사정알순기무제,관찰조급여사정알순화금수보효낭.대비치료후폐공능、6분종보행거리화SGRT평분등지표변화.결과 량조환자적폐공능、6MWD화SGRT균유소개선.관찰조치료후폐공능지표변화치균대우대조조,재6MWD상고우대조조,SGRT저우대조조,차이균유통계학의의(P＜0.01).경과2주적간예지후,량조제1초용력호기용적、제1초용력호기용적점예계치백분비,제1초용력호기용적/용력폐활량비교,관찰조적폐공능지표균호우대조조,차이균유통계학의의(P＜0.05).관찰조총유효솔위94.00％,대조조위78.00％.경x2검험,관찰조료효명현우우대조조,차이유통계학의의(x2=11.302,P＜0.05).결론 사정알순연합금수보효낭능명현개선은정기COPD환자폐공능각항지표、제고6분종보행거리,강저SGRT평분,감소기도조새정도,방지지기관경련,동시제고자신면역력,강저서약내약성급기불량반응.
Objective To inverstigate the effect of salbutamol combined with Jinshuibao capsules on pulmonary function,six minute walk test and SGRT in patients with chronic obstructive pulmonary disease(COPD).Methods One hundred patients with chronic obstructive pulmonary disease were randomly divided into experimental group and control group,the experimental group were given salbutamol aerosol.The control group were given salbutamol and Jinshuibao capsule.After treatment,lung function,six minutes walk distance and SGRT index change was compared.Results Lung function,6MWD and SGRT in the two groups were improved.But in the two groups,after treatment,lung function indexes changes in the control group were larger than those in the experimental group(P ＜0.01).The two groups after treatment,the 6MWD index in the control group is much lower than that in the experimental group (P ＜ 0.01).But SGRT in the control group was higher than that in the test group (P ＜ 0.01).The total efficiency of the patients in the observation group was 94％ ; the total effective rate of the control group patients was 78％.The clinical effects of two groups were tested by x2 test,the curative effect in observation group were significantly better than that in the control group,there was statistically significant differences (x2 =11.302,P ＜ 0.05).Conclusions Salbutamol combined with Jinshuibao capsule can obviously improve lung function indicators of patients with COPD,improve six minutes walking distance,degree of SGRT,reduce the degree of airway obstruction,prevent bronchospasm,and enhance the immunity,reduce drug resistance and adverse reaction.
