CAJ | 학술논문

目的分析感染人工关节的病原菌和药敏结果,为临床治疗人工关节置换术后感染提供依据.方法选取2011年5月-2012年3月我院收治的人工关节置换术后感染病例,将其中培养的70株病原菌和相对应的药敏结果进行分析.结果主要病原菌依次为凝固酶阴性葡萄球菌(37.14%)、金黄色葡萄球菌(15.71%)、革兰阳性杆菌(8.57%)、铜绿假单胞菌(5.71%)、表皮葡萄球菌(5.71%)、大肠埃希菌(4.29%)等.细菌对万古霉素、力奈唑烷及亚胺培南最为敏感,红霉素、青霉素、阿莫西林、复方新诺明耐药比例很高.结论感染人工关节的细菌以革兰阳性菌多见,可首选万古霉素、利奈唑烷和(或)亚胺培南进行治疗,然后再根据药敏结果进行调整.
목적분석감염인공관절적병원균화약민결과,위림상치료인공관절치환술후감염제공의거.방법선취2011년5월-2012년3월아원수치적인공관절치환술후감염병례,장기중배양적70주병원균화상대응적약민결과진행분석.결과주요병원균의차위응고매음성포도구균(37.14%)、금황색포도구균(15.71%)、혁란양성간균(8.57%)、동록가단포균(5.71%)、표피포도구균(5.71%)、대장애희균(4.29%)등.세균대만고매소、력내서완급아알배남최위민감,홍매소、청매소、아막서림、복방신낙명내약비례흔고.결론감염인공관절적세균이혁란양성균다견,가수선만고매소、리내서완화(혹)아알배남진행치료,연후재근거약민결과진행조정.
Objective To provide the evidence for infected joints after artificial joint replacement by analyzing the bacteria infecting artificial joints and their drug sensitivity. Methods Seventy strains isolated from bloodsamples of patients with infection after artificial joint replacement (admitted to our hospital from May 2011 to March 2012) and their drug sensitivity were retrospectively analyzed. Results The major bacteria infecting joints after artificial joint replacement were coagulase-negative staphylococci followed by staphy-lococcus aureus, Gram-positive bacilli, Pseudomonas aeruginosa, staphylococcus epidermidis, and Escherichia coli, accounting for 37.14%, 15.71%, 8.57%, 5.71%, 5.71% and 4.29% respectively. These bacteria were most sensitive to vancomycin, linezolid, imipenem and highly resistant to erythrocin, penicillin, amoxicillin and cotrimoxazole. Conclusion Bacteria infecting artificial joints are mainly the Gram-positive bacteria. Vancomycin, linezolid and (or) imipenem are the first choice of treatment for infected joints after artificial joint replacement, which should be adjusted according to their drug sensitivity.