解放军医学院学报
解放軍醫學院學報
해방군의학원학보
Academic Journal of Chinese Pla Medical School
2013年
3期
201-203
,共3页
高中宝%赵杏丽%王炜%尚延昌%时霄冰%柏秀娟%郭艳娥%王振福%吴卫平
高中寶%趙杏麗%王煒%尚延昌%時霄冰%柏秀娟%郭豔娥%王振福%吳衛平
고중보%조행려%왕위%상연창%시소빙%백수연%곽염아%왕진복%오위평
老年人%脑微出血%脑小血管病%危险因素
老年人%腦微齣血%腦小血管病%危險因素
노년인%뇌미출혈%뇌소혈관병%위험인소
aged%cerebral microbleeds%small vessel disease%risk factors
目的分析老年患者脑微出血(cerebral microbleeds,CMBs)的分布特点及相关危险因素.方法搜集2010年2月-2012年2月本科住院患者217例,年龄60~96(81±6)岁.采集病史及实验室资料,签署知情同意.采用GE公司1.5T扫描仪行常规磁共振及三维梯度回波序列检查,分别记录各个脑叶及脑区的CMBs病灶数.结果本组CMBs检出率为39.2%,随年龄增长CMBs的检出率逐步增高.皮层CMBs病灶多位于额颞叶,深部CMBs病灶多见于深部白质和丘脑.单因素分析显示年龄、高血压病、脑出血史及脑梗死史是CMBs的危险因素.分层分析显示年龄(OR 1.677,95%CI 1.061~2.652, P=0.027)、高血压病(OR 5.415,95%CI 1.723~17.016,P=0.004)及脑出血史(OR 4.065,95%CI 1.129~14.629,P=0.032)与皮层CMBs密切相关.脑梗死史(OR 3.376,95%CI 1.661~6.863,P=0.001)是深部CMBs的独立危险因素.结论不同部位的CMBs相关危险因素不同.
目的分析老年患者腦微齣血(cerebral microbleeds,CMBs)的分佈特點及相關危險因素.方法搜集2010年2月-2012年2月本科住院患者217例,年齡60~96(81±6)歲.採集病史及實驗室資料,籤署知情同意.採用GE公司1.5T掃描儀行常規磁共振及三維梯度迴波序列檢查,分彆記錄各箇腦葉及腦區的CMBs病竈數.結果本組CMBs檢齣率為39.2%,隨年齡增長CMBs的檢齣率逐步增高.皮層CMBs病竈多位于額顳葉,深部CMBs病竈多見于深部白質和丘腦.單因素分析顯示年齡、高血壓病、腦齣血史及腦梗死史是CMBs的危險因素.分層分析顯示年齡(OR 1.677,95%CI 1.061~2.652, P=0.027)、高血壓病(OR 5.415,95%CI 1.723~17.016,P=0.004)及腦齣血史(OR 4.065,95%CI 1.129~14.629,P=0.032)與皮層CMBs密切相關.腦梗死史(OR 3.376,95%CI 1.661~6.863,P=0.001)是深部CMBs的獨立危險因素.結論不同部位的CMBs相關危險因素不同.
목적분석노년환자뇌미출혈(cerebral microbleeds,CMBs)적분포특점급상관위험인소.방법수집2010년2월-2012년2월본과주원환자217례,년령60~96(81±6)세.채집병사급실험실자료,첨서지정동의.채용GE공사1.5T소묘의행상규자공진급삼유제도회파서렬검사,분별기록각개뇌협급뇌구적CMBs병조수.결과본조CMBs검출솔위39.2%,수년령증장CMBs적검출솔축보증고.피층CMBs병조다위우액섭협,심부CMBs병조다견우심부백질화구뇌.단인소분석현시년령、고혈압병、뇌출혈사급뇌경사사시CMBs적위험인소.분층분석현시년령(OR 1.677,95%CI 1.061~2.652, P=0.027)、고혈압병(OR 5.415,95%CI 1.723~17.016,P=0.004)급뇌출혈사(OR 4.065,95%CI 1.129~14.629,P=0.032)여피층CMBs밀절상관.뇌경사사(OR 3.376,95%CI 1.661~6.863,P=0.001)시심부CMBs적독립위험인소.결론불동부위적CMBs상관위험인소불동.
Objective To study the distribution of cerebral microbleeds (CMBs) in elderly patients and its related risk factors. Methods Medical records and laboratory test data of 217 elderly patients aged 60-96 years admitted to our department from February 2010 to February 2012 were collected. The patients underwent MRI and routine laboratory tests. The number of CMBs in their brain was recorded. Results The detection rate of CMBs was 39.2%, which increased with the age of patients. The CMBs were mainly located in frontotemporal lobe, white matter and thalamus. Single factor analysis showed that age, hypertension, cerebral hemorrhage and infarction history were the risk factors for CMBs. Logistic analysis showed that age (OR=1.677, 95%CI:1.061-2.652, P=0.027), hypertension (OR=5.415, 95%CI:1.723-17.016, P=0.004) and cerebral hemorrhage history (OR=4.065, 95%CI:1.129-14.629, P=0.032) were closely related with CMBs. However, cerebral infarction history (OR=3.376, 95%CI:1.661-6.863, P=0.001) was an independent risk factor for CMBs. Conclusion The risk factors are different for CMBs at different locations.
