CAJ | 학술논문

目的对Sysmex CA1500全自动血凝仪纤维蛋白原测定方法Von Clauss法和PT‐der法的应用进行比较评价.方法对门诊及住院患者167例标本同时用Von Clauss法和PT‐der法测定,将结果按PT‐der法测定的纤维蛋白原(FIB)含量分为3个水平组进行比较,并进行统计学分析.结果对PT‐der法与Von Clauss法测定FIB含量进行比较,当FIB浓度在2.0~4.0 g/L时,两组结果差异无统计学意义(P>0.05).当FIB >4.0 g/L或<2.0 g/L时,差异有统计学意义(P<0.05).结论 Von Clauss法准确性高,特异性强,快速简便,但试剂昂贵,而PT‐der法不需另行独立测定,可节约试剂成本.实验室可将两种方法结合,这样既能保证结果的准确性,又保证检测速度,提高工作效率,节约成本.
목적대Sysmex CA1500전자동혈응의섬유단백원측정방법Von Clauss법화PT‐der법적응용진행비교평개.방법대문진급주원환자167례표본동시용Von Clauss법화PT‐der법측정,장결과안PT‐der법측정적섬유단백원(FIB)함량분위3개수평조진행비교,병진행통계학분석.결과대PT‐der법여Von Clauss법측정FIB함량진행비교,당FIB농도재2.0~4.0 g/L시,량조결과차이무통계학의의(P>0.05).당FIB >4.0 g/L혹<2.0 g/L시,차이유통계학의의(P<0.05).결론 Von Clauss법준학성고,특이성강,쾌속간편,단시제앙귀,이PT‐der법불수령행독립측정,가절약시제성본.실험실가장량충방법결합,저양기능보증결과적준학성,우보증검측속도,제고공작효솔,절약성본.
Objective To evalute two different methods of fibrinogen assay by the automatic coagulometer of Sysmex CA1500 .Methods Von Clauss method and PT‐der method were used to detect 167 clinical samples .FIB was divided into 3 groups based on the results of PT‐der method .The result of FIB was analyzed by statistical method . Results Compare with two methods of PT‐der and Von Clauss ,there was not statistically significant difference (P>0 .05) when the concentration of fibrinogen was between 2 .0 -4 .0 g/L .When the concentration of fibrinogen was lower than 2 .0 g/L or higher than 4 .0 g/L ,the two methods had statistically significant difference (P<0 .05) .Con‐clusion Von Clauss has high veracity ,it is a fast and simple method ,but the reagent is very expansive .PT‐der meth‐od don't any reagent ,so the cost is low .The combination of the two methods can make sure that works are good quali‐ty and rapid ,improve efficiency ,and reduce the reagent cost .