检验医学与临床
檢驗醫學與臨床
검험의학여림상
JOURNAL OF LABORATORY MEDICINE AND CLINICAL SCIENCES
2013年
1期
60
,共1页
慢性乙型肝炎%中性粒细胞%趋化指数%超氧化物歧化酶%丙二醛%脂质过氧化
慢性乙型肝炎%中性粒細胞%趨化指數%超氧化物歧化酶%丙二醛%脂質過氧化
만성을형간염%중성립세포%추화지수%초양화물기화매%병이철%지질과양화
chronic hepatitis B%neutrophil%chemotactic index%superoxide dismutase%malonyldialde‐hyde
目的探讨慢性乙型肝炎患者中性粒细胞趋化功能与脂质过氧化的关系.方法应用琼脂糖淀胶玻片法和化学比色法对102例慢性乙型肝炎患者进行中性粒细胞趋化功能测定和超氧化物歧化酶(SOD)、丙二醛(MDA)水平检测,并与35例健康人作比较.结果各型慢性乙型肝炎患者趋化指数和SOD水平均低于健康对照组(P<0.01),而MDA水平高于健康对照组(P<0.01),血清SOD水平与MDA水平呈显著负相关(r=-0.4684, P<0.01),结论慢性乙型肝炎患者中性粒细胞趋化功能的降低与脂质过氧化有一定的相关性.
目的探討慢性乙型肝炎患者中性粒細胞趨化功能與脂質過氧化的關繫.方法應用瓊脂糖澱膠玻片法和化學比色法對102例慢性乙型肝炎患者進行中性粒細胞趨化功能測定和超氧化物歧化酶(SOD)、丙二醛(MDA)水平檢測,併與35例健康人作比較.結果各型慢性乙型肝炎患者趨化指數和SOD水平均低于健康對照組(P<0.01),而MDA水平高于健康對照組(P<0.01),血清SOD水平與MDA水平呈顯著負相關(r=-0.4684, P<0.01),結論慢性乙型肝炎患者中性粒細胞趨化功能的降低與脂質過氧化有一定的相關性.
목적탐토만성을형간염환자중성립세포추화공능여지질과양화적관계.방법응용경지당정효파편법화화학비색법대102례만성을형간염환자진행중성립세포추화공능측정화초양화물기화매(SOD)、병이철(MDA)수평검측,병여35례건강인작비교.결과각형만성을형간염환자추화지수화SOD수평균저우건강대조조(P<0.01),이MDA수평고우건강대조조(P<0.01),혈청SOD수평여MDA수평정현저부상관(r=-0.4684, P<0.01),결론만성을형간염환자중성립세포추화공능적강저여지질과양화유일정적상관성.
Objective To explore the relationship of detection of neutrophilic chemotactic function and serum lipid peroxidation injury in patients with chronic hepatitis B .Methods Neutrophilic chemotactic function ,serum SOD ,MDA(with chemistry) levels were detected in 102 cases with chronic hepatitis B and 35 controls . Results Neutrophilic chemotactic indexes and sercm SOD levels were significantly lower than those in controls (P<0 .01) ,but serum MDA levels were significantly higher than controls (P<0 .01) ,serum SOD levels were negatively correlated with MDA levels (r= -0 .468 4) .Conclusion The neutrophilic chemotactic function decreasing in patients with chronic hepatitis B can be closely related to lipid peroxidation injury .
