上海医药
上海醫藥
상해의약
SHANGHAI MEDICAL & PHARMACEUTICAL JOURNAL
2013年
6期
8-11
,共4页
21-三体综合征%无创性产前诊断%核型分析%胎儿细胞
21-三體綜閤徵%無創性產前診斷%覈型分析%胎兒細胞
21-삼체종합정%무창성산전진단%핵형분석%태인세포
21-trisomy syndrome%noninvasive prenatal diagnosis%karyotype analysis%fetal cells
无创性产前诊断技术在近10年取得了较快的进展,通过母体外周血获取胎儿细胞、游离DNA或mRNA,利用表观遗传学手段,对胎源性信息进行产前筛查,获得对21号染色体非整倍体信息的判断.该项技术具有无创、快速、高效的优点,但目前应用仍存在一定的局限性.随着该技术的不断成熟,它的应用前景是非常广阔的.
無創性產前診斷技術在近10年取得瞭較快的進展,通過母體外週血穫取胎兒細胞、遊離DNA或mRNA,利用錶觀遺傳學手段,對胎源性信息進行產前篩查,穫得對21號染色體非整倍體信息的判斷.該項技術具有無創、快速、高效的優點,但目前應用仍存在一定的跼限性.隨著該技術的不斷成熟,它的應用前景是非常廣闊的.
무창성산전진단기술재근10년취득료교쾌적진전,통과모체외주혈획취태인세포、유리DNA혹mRNA,이용표관유전학수단,대태원성신식진행산전사사,획득대21호염색체비정배체신식적판단.해항기술구유무창、쾌속、고효적우점,단목전응용잉존재일정적국한성.수착해기술적불단성숙,타적응용전경시비상엄활적.
@@@@A rapid progress has been made in noninvasive prenatal diagnostic technology in last 10 years. People obtain fetal cells, free fetal DNA or mRNA through maternal peripheral blood and take advantage of epigenetic means to do prenatal screening and access the information of chromosome 21 aneuploidy. It is obvious to see that the advantage of NIPD is noninvansive, rapid and efficient. At present its application exists certain limitation. With the technology of the NIPD continuing to be matured, its application is very broad prospects.
