世界最新医学信息文摘(电子版)
世界最新醫學信息文摘(電子版)
세계최신의학신식문적(전자판)
World Latest Medicine Information
2013年
1期
7-8
,共2页
乙型肝炎病毒%Pre-S1Ag%HBeAg%HBV-DNA%病毒复制
乙型肝炎病毒%Pre-S1Ag%HBeAg%HBV-DNA%病毒複製
을형간염병독%Pre-S1Ag%HBeAg%HBV-DNA%병독복제
目的分析乙型肝炎病毒(HBV)感染患者中血清Pre-S1Ag、HBV-DNA与HBVM的关系及临床意义.方法收集本院慢性乙肝病毒肝炎患者血清标本343例,应用PCR法检测HBV-DNA含量,ELISA法检测Pre-S1Ag、HBVM.结果343份标本中HBV-DNA阳性率为84.2%(289/343),Pre-S1Ag阳性率为79.6%(273/343),HBeAg阳性率为65.1%(223/343).HBV-DNA与Pre-S1Ag的阳性率无统计学差异、与HBeAg的阳性率差异有统计学意义.120例HBeAg阴性的标本中79例Pre-S1Ag阳性,49例HBV-DNA阳性,两者阳性率差异无统计学意义.结论Pre-S1Ag是一项十分重要的诊断乙肝病毒复制的指标.
目的分析乙型肝炎病毒(HBV)感染患者中血清Pre-S1Ag、HBV-DNA與HBVM的關繫及臨床意義.方法收集本院慢性乙肝病毒肝炎患者血清標本343例,應用PCR法檢測HBV-DNA含量,ELISA法檢測Pre-S1Ag、HBVM.結果343份標本中HBV-DNA暘性率為84.2%(289/343),Pre-S1Ag暘性率為79.6%(273/343),HBeAg暘性率為65.1%(223/343).HBV-DNA與Pre-S1Ag的暘性率無統計學差異、與HBeAg的暘性率差異有統計學意義.120例HBeAg陰性的標本中79例Pre-S1Ag暘性,49例HBV-DNA暘性,兩者暘性率差異無統計學意義.結論Pre-S1Ag是一項十分重要的診斷乙肝病毒複製的指標.
목적분석을형간염병독(HBV)감염환자중혈청Pre-S1Ag、HBV-DNA여HBVM적관계급림상의의.방법수집본원만성을간병독간염환자혈청표본343례,응용PCR법검측HBV-DNA함량,ELISA법검측Pre-S1Ag、HBVM.결과343빈표본중HBV-DNA양성솔위84.2%(289/343),Pre-S1Ag양성솔위79.6%(273/343),HBeAg양성솔위65.1%(223/343).HBV-DNA여Pre-S1Ag적양성솔무통계학차이、여HBeAg적양성솔차이유통계학의의.120례HBeAg음성적표본중79례Pre-S1Ag양성,49례HBV-DNA양성,량자양성솔차이무통계학의의.결론Pre-S1Ag시일항십분중요적진단을간병독복제적지표.
@@@@Objective Analysis the clinical significance of Pre-S1Ag,HBV-DNA and HBVM in patients with hepatitis B virus(HBV)infection. Method A total of 343 chronic hepatitis B patients have been collected.HBV maker and Pre-S1Ag were detected by ELISA,and HBV-DNA by PCR. Result The positive rate of HBV-DNA was 84.2%among the 343 patients, and Pre-S1Ag was 79.6%,HBeAg was 65.1%.there is no significant difference between HBV-DNA and Pre-S1Ag,but there is significant difference between HBV-DNA and HBeAg. The positive rate of Pre-S1Ag was 65.8%among the 120 patients whose HBeAg were negative,and HBV-DNA was 40.8%,there is no significant difference between Pre-S1Ag and HBeAg. Conclu-sion Pre-S1Ag is a valuable marker for HBV replication.
