物理学报
物理學報
물이학보
2013年
8期
084708-1-084708-7
,共1页
梁金福%陈伟中?%邵纬航%周超%杜联芳%金利芳
樑金福%陳偉中?%邵緯航%週超%杜聯芳%金利芳
량금복%진위중?%소위항%주초%두련방%금리방
包膜微泡%锁相积分拍摄方法%频谱
包膜微泡%鎖相積分拍攝方法%頻譜
포막미포%쇄상적분박섭방법%빈보
encapsulated microbubbles%lock-in integrate imaging method%spectra
运用长距离显微成像系统与锁相积分拍摄技术相结合的方法,拍到了单个造影剂微泡在两种不同频率和不同声压下的周期性振动图像.根据这些图像得到了微泡直径的实验数据,并分别用Hoff模型和Rayleigh-Plesset模型对数据进行拟合,并对数据进行了频谱分析.结果表明:Hoff模型对实验数据的拟合结果优于Rayleigh-Plesset模型的拟合结果;二次谐波的相对强度随着声压幅度的升高而增大.
運用長距離顯微成像繫統與鎖相積分拍攝技術相結閤的方法,拍到瞭單箇造影劑微泡在兩種不同頻率和不同聲壓下的週期性振動圖像.根據這些圖像得到瞭微泡直徑的實驗數據,併分彆用Hoff模型和Rayleigh-Plesset模型對數據進行擬閤,併對數據進行瞭頻譜分析.結果錶明:Hoff模型對實驗數據的擬閤結果優于Rayleigh-Plesset模型的擬閤結果;二次諧波的相對彊度隨著聲壓幅度的升高而增大.
운용장거리현미성상계통여쇄상적분박섭기술상결합적방법,박도료단개조영제미포재량충불동빈솔화불동성압하적주기성진동도상.근거저사도상득도료미포직경적실험수거,병분별용Hoff모형화Rayleigh-Plesset모형대수거진행의합,병대수거진행료빈보분석.결과표명:Hoff모형대실험수거적의합결과우우Rayleigh-Plesset모형적의합결과;이차해파적상대강도수착성압폭도적승고이증대.
@@@@Using a long-distance microscope imaging system and a lock-in phase integrate technique, optical measurements demonstrate that the evolutional behaviors of a phospholipid-shelled micro-bubble, a kind of ultrasound contrast agent, under two ultrasound frequencies and different pressures. Dozens of frames of an oscillating microbubble for one acoustic cycle are captured. The experimental data of micro-bubble diameter are fit by the numerical calculations of the Hoff model and the Rayleigh-Plesset model, respectively. The results show the good agreement between experimental data and the theoretical calculation in the Hoff model. In addition, the spectral analysis based on the experimental data indicates that the relative intensity of the second harmonic increases with the driving pressure amplitude.