中国化工贸易
中國化工貿易
중국화공무역
CHINA CHEMICAL TRADE
2013年
3期
139
,共1页
α-生育酚琥珀酸酯%合成%酯化反应
α-生育酚琥珀痠酯%閤成%酯化反應
α-생육분호박산지%합성%지화반응
本文研究了以乙二胺为催化剂,由α-生育酚和琥珀酸酐合成α-生育酚琥珀酸酯(α-TOS)的酯化反应工艺.实验结果表明用酯类溶剂有利于反应的顺利进行.本实验采用了乙酸异丁酯为溶剂,以乙二胺为催化剂的情况下使α-生育酚和琥珀酸酐反应.增大乙二胺的用量,提高琥珀酸酐与α-生育酚的配比有利于转化率的提高,但反应温度的提高,在一定范围内对转化率的提高影响不大,当大于60℃时随温度的升高转化率明显提高.实验得出α-生育酚与琥珀酸酐反应的较好工艺条件下,转化率达81.2%.
本文研究瞭以乙二胺為催化劑,由α-生育酚和琥珀痠酐閤成α-生育酚琥珀痠酯(α-TOS)的酯化反應工藝.實驗結果錶明用酯類溶劑有利于反應的順利進行.本實驗採用瞭乙痠異丁酯為溶劑,以乙二胺為催化劑的情況下使α-生育酚和琥珀痠酐反應.增大乙二胺的用量,提高琥珀痠酐與α-生育酚的配比有利于轉化率的提高,但反應溫度的提高,在一定範圍內對轉化率的提高影響不大,噹大于60℃時隨溫度的升高轉化率明顯提高.實驗得齣α-生育酚與琥珀痠酐反應的較好工藝條件下,轉化率達81.2%.
본문연구료이을이알위최화제,유α-생육분화호박산항합성α-생육분호박산지(α-TOS)적지화반응공예.실험결과표명용지류용제유리우반응적순리진행.본실험채용료을산이정지위용제,이을이알위최화제적정황하사α-생육분화호박산항반응.증대을이알적용량,제고호박산항여α-생육분적배비유리우전화솔적제고,단반응온도적제고,재일정범위내대전화솔적제고영향불대,당대우60℃시수온도적승고전화솔명현제고.실험득출α-생육분여호박산항반응적교호공예조건하,전화솔체81.2%.
Catalyzed by ethylenediamine,the esterification of α-Tocopheryl succinate (α-TOS) with and suecinic anhydride were stud-ied.The experimental resultα-Tocopherol s show that solvent with esters is good for the reaction. In this experiment,we use isobutyl acetate and ethylenediamine for the esterification ofα-Tocopheryl succinate (α-TOS) withα-Tocopherol and suecinic anhydride. Increasing the dosage of ethylenediamine and the ratio of suecinic anhydride and α-Tocopherol are propitious to improve the conversion rate of reaction,but when the temperature is less than 60℃, temperature has not distinctness effect to conversion rate.For the experimental,we can see under the preferable con-dention the conversion rate is 81.2%.
