CAJ | 학술논문

目的探讨听神经瘤手术效果及治疗策略选择.方法回顾性分析2001年1月至2010年12月共594例听神经瘤患者所采用治疗策略及其中461例手术效果.结果594例患者中,管内/小型、中/中大型、大/巨型听神经瘤分别占25.6%、55.1%和19.3%,随访观察、立体定向放疗和手术率分别为25.3%、6.9%、77.6%.461例手术患者中,肿瘤全切、近全切、次全切率分别为95.9%、3.0%、1.1%,面神经解剖保留94.4%,术后短期和长期面神经功能良好率为69.8%和79.0%,术后听力保留率41.4%,听力良好率23.4%,手术死亡率0.2%,后组颅神经麻痹和脑脊液漏率分别为3.9%和3.3%,复发率为2.2%.结论手术仍为听神经瘤主要治疗策略,其效果令人满意,而听神经瘤早期诊断将促进治疗策略的改变.
목적탐토은신경류수술효과급치료책략선택.방법회고성분석2001년1월지2010년12월공594례은신경류환자소채용치료책략급기중461례수술효과.결과594례환자중,관내/소형、중/중대형、대/거형은신경류분별점25.6%、55.1%화19.3%,수방관찰、입체정향방료화수술솔분별위25.3%、6.9%、77.6%.461례수술환자중,종류전절、근전절、차전절솔분별위95.9%、3.0%、1.1%,면신경해부보류94.4%,술후단기화장기면신경공능량호솔위69.8%화79.0%,술후은력보류솔41.4%,은력량호솔23.4%,수술사망솔0.2%,후조로신경마비화뇌척액루솔분별위3.9%화3.3%,복발솔위2.2%.결론수술잉위은신경류주요치료책략,기효과령인만의,이은신경류조기진단장촉진치료책략적개변.
Objective To report surgical outcomes and management strategies in acoustic neuroma. Methods Man?agement strategies and surgical outcomes in 594 patients with sporadic acoustic neuroma (461 surgical procedures) treated from January 2001 to December 2010 were retrospectively reviewed. Results The rate of intracanal/small, medium/moder?ately large and large/giant tumors was 25.6%, 55.1%and 19.3%respectively in the 594 cases. The rate of“wait and scan”, radiotherapy and surgery in this group was 25.3%, 6.9% and 77.6% respectively. Of the 461 surgeries, the rate of total, near-total and subtotal removal was 95.9%, 3.0%and 1.1%, respectively. The rate of intraoperative anatomical preserva?tion of the facial nerve (FN) was 94.4%. Short-term and long-term good FN function rates were 69.8%and 79.0%. The rate of hearing preservation and useful hearing were 41.4%and 23.4%. The mortality rate was 0.2%. The rates of lower cranial nerve palsy and cerebrospinal fluid leakage were 3.9%and 3.3%. Recurrence rate was 2.2%. Conclusions Surgical resec?tion is still the main management approach in acoustic neuroma, with satisfactory outcomes. The management strategy may be changed by early diagnosis of tumor.