CAJ | 학술논문

近年来,海洋真菌因其能够产生大量结构新颖、活性显著的代谢产物而受到广泛关注.本文综述了1991—2010年间从海洋真菌分离得到的134个新吲哚生物碱的结构和活性研究情况,其中包括fumitremorgin类19个、notoamide类22个、细胞松弛素类18个、吲哚喹唑啉类9个、吲哚萜类11个、肽类及其他单吲哚类21个和双吲哚类化合物34个.海洋真菌来源的吲哚生物碱不仅结构奇特,并且表现出多种重要的生物活性,具有潜在的研究和应用价值.
근년래,해양진균인기능구산생대량결구신영、활성현저적대사산물이수도엄범관주.본문종술료1991—2010년간종해양진균분리득도적134개신신타생물감적결구화활성연구정황,기중포괄fumitremorgin류19개、notoamide류22개、세포송이소류18개、신타규서람류9개、신타첩류11개、태류급기타단신타류21개화쌍신타류화합물34개.해양진균래원적신타생물감불부결구기특,병차표현출다충중요적생물활성,구유잠재적연구화응용개치.
@@@@In recent years, marine natural products of fungal origin have gained considerable recognition, as many of them possess novel structures and interesting biological and pharmacological properties. This review includes 134 indole alkaloids of marine-derived fungi with their structures and activities published during 1991?2010. Of the indole alkaloids, there were 19 fumitremorgins, 22 notoamides, 18 cytochalasans, 9 fumiquinazolines, 11 indole terpenes, 21 peptides and other single indole alkaloids, and 34 bisindole alkaloids. These indole alkaloids showed not only unique structures but also a variety of important biological activities and had potential values in application.