CAJ | 학술논문

目的:探讨角膜缘干细胞移植术中联合丝裂霉素C治疗翼状胬肉的治疗效果.方法:对474例(492眼)采用3种不同术式分3组行手术治疗.Ⅰ组:单纯翼状胬肉切除术;Ⅱ组:翼状胬肉切除术+自体角膜缘干细胞移植术;Ⅲ组:翼状胬肉切除术+自体角膜缘干细胞移植术+丝裂霉素C.经过6个月~5年的对比观察.结果:3种术式比较:单纯翼状胬肉切除术92眼,治愈62眼,复发30眼,复发率32.6%;翼状胬肉切除术+自体角膜缘干细胞移植术119眼,治愈104眼,复发15眼,复发率12.6%;翼状胬肉切除术+自体角膜缘干细胞移植术+丝裂霉素 C 手术281眼,治愈276眼,复发5眼,复发率1.8%.结论:翼状胬肉切除术+自体角膜缘干细胞移植术+丝裂霉素C治疗翼状胬肉复发率明显低于其他术式,且术后角、结膜上皮修复快,视力恢复好.
목적:탐토각막연간세포이식술중연합사렬매소C치료익상노육적치료효과.방법:대474례(492안)채용3충불동술식분3조행수술치료.Ⅰ조:단순익상노육절제술;Ⅱ조:익상노육절제술+자체각막연간세포이식술;Ⅲ조:익상노육절제술+자체각막연간세포이식술+사렬매소C.경과6개월~5년적대비관찰.결과:3충술식비교:단순익상노육절제술92안,치유62안,복발30안,복발솔32.6%;익상노육절제술+자체각막연간세포이식술119안,치유104안,복발15안,복발솔12.6%;익상노육절제술+자체각막연간세포이식술+사렬매소 C 수술281안,치유276안,복발5안,복발솔1.8%.결론:익상노육절제술+자체각막연간세포이식술+사렬매소C치료익상노육복발솔명현저우기타술식,차술후각、결막상피수복쾌,시력회복호.
@@@@Objective:Analyze the clinical efficacy of surgical method to treat pterygium by pterygium excision with limbal autograft transplantation with mitomycin C in the operation. Methods:474 (492 eyes)pterygium patients admitted in our hospital, according to different surgical methods were divided into three groups: Ⅰ group: simple excision of pterygium, Ⅱ group: pterygium excision combined with limbal autograft transplantation, Ⅲ: pterygium excision with limbal autograft transplantation with mitomycin C in the operation, Followed up for 6 months to 36 months.Record postoperative recurrence of pterygium, corneal epithelial healing time and postoperative visual acuity, Statistical analysis of differences results of each surgical method.Results: The comparison of the recurrence rate of different pterygium group: Ⅰ group(92 eyes) had 30 eyes recurrence, the recurrence rate was 32.6%; Ⅱ group(119 eyes) had 15 eyes recurrence ,the recurrence rate was 12.6%; Ⅲ group(281 eyes) had 5 eye recurrence, the recurrence rate of 1.8%. After statistical analysis, the recurrence rate among the three groups has significant difference. Conclusions: Pterygium excision with limbal autograft transplantation with mitomycin C in the operation is a better treatment to lower the recurrence rate of pterygium and better improvement visual acuity and corneal epithelial repair.