CAJ | 학술논문

目的探讨C反应蛋白(CRP)及胆红素水平与颈动脉粥样硬化程度的关系.方法原发性高血压患者90名,按颈动脉超声检测结果分为无斑块组和斑块组,将斑块组按回声强弱分为强回声组、弱回声组及混合回声组,比较各组间的CRP及胆红素.结果颈动脉粥样斑块随着回声增强,血清CRP水平增高,无斑块组和斑块组有显著差异(P<0.05),而斑块组间也有显著差异(P<0.05);斑块组血清胆红素水平低于无斑块组,无斑块组和斑块组有显著差异(P<0.05),但斑块组间无显著差异(P<0.05).结论原发性高血压患者颈动脉粥样硬化程度与CRP密切相关,颈动脉粥样斑块形成可能与低血清胆红素有关.
목적탐토C반응단백(CRP)급담홍소수평여경동맥죽양경화정도적관계.방법원발성고혈압환자90명,안경동맥초성검측결과분위무반괴조화반괴조,장반괴조안회성강약분위강회성조、약회성조급혼합회성조,비교각조간적CRP급담홍소.결과경동맥죽양반괴수착회성증강,혈청CRP수평증고,무반괴조화반괴조유현저차이(P<0.05),이반괴조간야유현저차이(P<0.05);반괴조혈청담홍소수평저우무반괴조,무반괴조화반괴조유현저차이(P<0.05),단반괴조간무현저차이(P<0.05).결론원발성고혈압환자경동맥죽양경화정도여CRP밀절상관,경동맥죽양반괴형성가능여저혈청담홍소유관.
@@@@ Objective To explore the association of C-reactive protein and serum bilirubin with carotid athersclerosis in patients with primary hypertension.Method 90 patients with primary hypertension whose carotid arteries were detected by ultrasound were divided into non-atheroma group and atheroma group.The atheroma group which detected by the grade of the ultrasound of the atheroma were divided into weak group,mixed group and hard group.Their serum c-reactive protein and serum bilirubin levels were measured and compared.Results Th ose with higher levels of serum c-reactive protein and lower serum bilirubin showed more severe carotid arthersclerosis(P<0.05).And C-reactive protein were different among the atheroma group (P<0.05),while the serum bilirubin were no different among them(P>0.05).Conclusions Serum C-reactive protein levels might be closely related to athersclerosls and the fomation of carotid plaque might be related to low levels of serum bilirubin.