医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2013年
7期
138-140
,共3页
陆明%范国荣%陈桂良%陈祝康%杨美成%汪杨
陸明%範國榮%陳桂良%陳祝康%楊美成%汪楊
륙명%범국영%진계량%진축강%양미성%왕양
氢氯噻嗪%测量不确定度%高效液相色谱法
氫氯噻嗪%測量不確定度%高效液相色譜法
경록새진%측량불학정도%고효액상색보법
Hydrochlorothiazide measurement uncertainty%High Performance%Liquid Chromatography
目的:对高效液相色谱法测定复方卡托普利片中氢氯噻嗪含量不确定度进行评定分析.方法:按照中国药典2010年版二部复方卡托普利片检验方法对氢氯噻嗪含量进行测定.根据《测量不确定度评定与表示》(JJF1059-1999)中有关规定对测量结果中带来的各个不确定度进行分析、评定和量化.结果:量化各个不确定度分量,提出了该法的合成不确定度评估结果.结论:该法测定氢氯噻嗪含量的相对扩展不确定度U=0.08%(k=2).
目的:對高效液相色譜法測定複方卡託普利片中氫氯噻嗪含量不確定度進行評定分析.方法:按照中國藥典2010年版二部複方卡託普利片檢驗方法對氫氯噻嗪含量進行測定.根據《測量不確定度評定與錶示》(JJF1059-1999)中有關規定對測量結果中帶來的各箇不確定度進行分析、評定和量化.結果:量化各箇不確定度分量,提齣瞭該法的閤成不確定度評估結果.結論:該法測定氫氯噻嗪含量的相對擴展不確定度U=0.08%(k=2).
목적:대고효액상색보법측정복방잡탁보리편중경록새진함량불학정도진행평정분석.방법:안조중국약전2010년판이부복방잡탁보리편검험방법대경록새진함량진행측정.근거《측량불학정도평정여표시》(JJF1059-1999)중유관규정대측량결과중대래적각개불학정도진행분석、평정화양화.결과:양화각개불학정도분량,제출료해법적합성불학정도평고결과.결론:해법측정경록새진함량적상대확전불학정도U=0.08%(k=2).
@@@@Objective: To analyze the measurement uncertainty in determination of Hydrochlorothiazide in Compound Captopril Tablets with HPLC. Methods: The assay of Hydrochlorothiazide was detected in accordance with the Pharmacopoeia of the People’s Republic of China.2010ed.Volume 2, and the measurement uncertainty was evaluated according to JJF1059-1999. Results: The expanded measurement uncertainties were quantified, and the evaluation results of measurement uncertainty was drawn. Conclusion: The expanded uncertainty was U=0.10% (k=2).
