CAJ | 학술논문

目的观察川芎嗪注射液联合黄芪注射液治疗早期糖尿病肾病的疗效.方法确诊的120例早期糖尿病肾病(DN)患者,给予川芎嗪注射液联合黄芪注射液静脉滴注2周,然后口服川芎嗪片和黄芪颗粒(无糖型)3个月,疗程结束后比较治疗前后尿微量白蛋白排泄率(UAER),血压、血脂,血糖等变化.结果治疗后 DN 早期患者 UAER 有显著降低(P <0.01).结论川芎嗪注射液联合黄芪注射液治疗早期糖尿病肾病疗效确切,且具有降压,改善糖脂代谢等多方面的有益作用,值得临床推广应用和深入研究.
목적관찰천궁진주사액연합황기주사액치료조기당뇨병신병적료효.방법학진적120례조기당뇨병신병(DN)환자,급여천궁진주사액연합황기주사액정맥적주2주,연후구복천궁진편화황기과립(무당형)3개월,료정결속후비교치료전후뇨미량백단백배설솔(UAER),혈압、혈지,혈당등변화.결과치료후 DN 조기환자 UAER 유현저강저(P <0.01).결론천궁진주사액연합황기주사액치료조기당뇨병신병료효학절,차구유강압,개선당지대사등다방면적유익작용,치득림상추엄응용화심입연구.
Objective To observe the clinic effect of Ligustrazine hydrochloride for injection combined Astragalus injection in early diabetic nephyropathy ( for short DN ) . Methods 120 cases treatment with Ligustrazine Hydrochloride for injection combined Astragalus injection for iv.drop for two weeks.then for oral tablets Ligustrazine Hydrochloride and Radix astragali granule ( sugar free form ) last for three months.UAER BP TG TC FBG were measured before and after treatment in al patients Results UAER was significantly decreased after treatment ( P<0.01). Conclusion Ligustrazine hydrochloride for injection combined Astragalus injction have a sagnificantly effet on early diabetic nephyropathy .alsohave benefit on lower BP and improved blood lipid blood glucose metabolism .It’s worthy of clinical application and further research.