中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2013年
12期
121-122
,共2页
肖憬%詹翔%桑圣刚%陈慧
肖憬%詹翔%桑聖剛%陳慧
초경%첨상%상골강%진혜
糖尿病肾病%白介素-8%白介素-10%尿微量白蛋白排泄率
糖尿病腎病%白介素-8%白介素-10%尿微量白蛋白排洩率
당뇨병신병%백개소-8%백개소-10%뇨미량백단백배설솔
Diabetic nephropathy%Interleukin-8%Interleukin-10%Urine albumin excretion rate
目的:探讨血清白细胞介素8、白细胞介素10水平的变化在糖尿病肾病发生、发展中的作用.方法:根据24 h尿微量白蛋白排泄率对2型DN患者分组,观察血清IL-8、IL-10水平的改变.结果:糖尿病3组的IL-8、IL-10水平均明显高于正常对照组,随糖尿病肾病的严重程度增加而增加,且与及血肌酐呈正相关.结论:检测血清IL-8、IL-10水平的变化可以作为临床观察DN病情及判断DM预后的参考指标.
目的:探討血清白細胞介素8、白細胞介素10水平的變化在糖尿病腎病髮生、髮展中的作用.方法:根據24 h尿微量白蛋白排洩率對2型DN患者分組,觀察血清IL-8、IL-10水平的改變.結果:糖尿病3組的IL-8、IL-10水平均明顯高于正常對照組,隨糖尿病腎病的嚴重程度增加而增加,且與及血肌酐呈正相關.結論:檢測血清IL-8、IL-10水平的變化可以作為臨床觀察DN病情及判斷DM預後的參攷指標.
목적:탐토혈청백세포개소8、백세포개소10수평적변화재당뇨병신병발생、발전중적작용.방법:근거24 h뇨미량백단백배설솔대2형DN환자분조,관찰혈청IL-8、IL-10수평적개변.결과:당뇨병3조적IL-8、IL-10수평균명현고우정상대조조,수당뇨병신병적엄중정도증가이증가,차여급혈기항정정상관.결론:검측혈청IL-8、IL-10수평적변화가이작위림상관찰DN병정급판단DM예후적삼고지표.
Objective:To investigate the significance of changes of serum IL-8 and IL-10 levels in the development of type 2 diabetic nephrosis. Method:The diabetic patients fell into three groups.Serum IL-8 and IL-10 levels were measured in type 2 diabetic patients and controls.Result:Serum levels of IL-8 and IL-10 were significantly higher in type 2 diabetes patients than those in controls and they increased in different stages of DN patients. There were positive correlations of serum IL-8,IL-10 with the concentration of Cr and UAER.Conclusion:Determination of serum IL-8 and IL-10 levels might be helpful for detection of diabetic nephropathy and monitoring the progress of the disease process.
