CAJ | 학술논문

目的:探讨采用综合措施阻断HIV/AIDS母婴垂直传播的效果.方法:选取2005年1月-2010年12月在笔者所在医院接受综合措施母婴阻断的HIV阳性孕妇107例为研究组,同期在广州市某医院产科的HIV阴性孕妇135例作为对照组.研究组采用HAART、剖宫产及新生儿出生时给予抗病毒药、人工喂养等综合措施进行母婴阻断,监测两组孕妇产前的肝功能、血常规、生化指标.研究组新生儿出生时及18个月龄时进行HIV检测.结果:研究组的107例新生儿出生时及18个月龄时检测HIV抗体均呈阴性.研究组孕妇白细胞、红细胞、血色素、球蛋白、空腹血糖与对照组比较,差异有统计学意义(P<0.05);两组血小板、甘油三酯、总胆固醇等指标比较差异无统计学意义(P>0.05).结论:采取孕产期前综合阻断措施,能有效降低HIV母婴垂直传播的发生率.
목적:탐토채용종합조시조단HIV/AIDS모영수직전파적효과.방법:선취2005년1월-2010년12월재필자소재의원접수종합조시모영조단적HIV양성잉부107례위연구조,동기재엄주시모의원산과적HIV음성잉부135례작위대조조.연구조채용HAART、부궁산급신생인출생시급여항병독약、인공위양등종합조시진행모영조단,감측량조잉부산전적간공능、혈상규、생화지표.연구조신생인출생시급18개월령시진행HIV검측.결과:연구조적107례신생인출생시급18개월령시검측HIV항체균정음성.연구조잉부백세포、홍세포、혈색소、구단백、공복혈당여대조조비교,차이유통계학의의(P<0.05);량조혈소판、감유삼지、총담고순등지표비교차이무통계학의의(P>0.05).결론:채취잉산기전종합조단조시,능유효강저HIV모영수직전파적발생솔.
Objective:To investigate the influence of combinative treatment for blockade of HIV mother-to-child transmission on HIV-infected pregnant patients.Methods:107 pregnant women identified with HIV infected were given combinative treatment for blockade of HIV mother-to-child transmission from Jan 2005 to Dec 2010.Their newborn babies were given anti-viral drug and artificial feeding.135 HIV negative pregnant women were chosen at random in a hospital of Guangzhou city as control group.Results:All the newborns babies were negative to HIV-Ab (ELISA) at the moment they were born and after 18 months.The WBC,RBC,Hb,and GLB were statistic significant differences between study group and control group(P<0.05),while the hemoglobin,albumin,glucose,total cholesterol,triglyceride were no significant differences between them(P>0.05).Conclusion:Combinative treatment could be effective to blockade of HIV mother-to-child transmission.