CAJ | 학술논문

目的:探讨腹腔引流导管联合吉非替尼控制癌性胸水的疗效.方法:以15例老年肺腺癌所致中量以上的胸腔积液患者为研究对象,所有患者均应用腹腔引流导管行胸腔闭式引流,同时予吉非替尼250 mg,口服,1次/d.结果:15例患者均一次置管成功,2例导管阻塞用肝素稀释液3 ml冲管后再通;1例导管脱落,1例导管外脱引流不畅重新置管,1例出现气胸经健侧卧位引流管抽气后吸收.经导管胸腔内注入高聚金葡素1~3次.所有患者经5~10 d置管,胸腔积液引流彻底.7例维持服药胸水完全控制;8例因药费高相继停药,胸水控制时间4~18个月.结论:腹腔引流导管闭式引流安全、损伤小,缓解症状迅速,联合吉非替尼长期控制癌性胸水疗效明确,但吉非替尼因费用高难以长期维持应用.
목적:탐토복강인류도관연합길비체니공제암성흉수적료효.방법:이15례노년폐선암소치중량이상적흉강적액환자위연구대상,소유환자균응용복강인류도관행흉강폐식인류,동시여길비체니250 mg,구복,1차/d.결과:15례환자균일차치관성공,2례도관조새용간소희석액3 ml충관후재통;1례도관탈락,1례도관외탈인류불창중신치관,1례출현기흉경건측와위인류관추기후흡수.경도관흉강내주입고취금포소1~3차.소유환자경5~10 d치관,흉강적액인류철저.7례유지복약흉수완전공제;8례인약비고상계정약,흉수공제시간4~18개월.결론:복강인류도관폐식인류안전、손상소,완해증상신속,연합길비체니장기공제암성흉수료효명학,단길비체니인비용고난이장기유지응용.
Objective:To explore the efficacy peritoneal drainage catheter combined with gefitinib to control malignant pleural effusion. Methods:15 elderly patients with lung adenocarcinoma patients with a large amount of pleural effusion in patients as research subjects. All patients underwent peritoneal drainage catheter closed thoracic drainage,while giving gefitinib 250 mg,orally,once/d. Results:15 patients were first catheter successful,2 cases of catheter obstruction with heparin diluents 3 ml red tube recanalization;1 case the catheter off and decathlete,1 patient pneumothorax contralateral supine drainage pipe exhaust and after cure. Through the catheter to inject high poly staphylococci 1 to 3 times,all patients by 5 to 10 days of catheterization,and thorough drainage of pleural effusion.7 patients remained medication,pleural effusion complete control,8 patients with high drug costs before and after stop medication,pleural effusion control time 4 to 18 months.Conclusion:Closed drainage of the abdominal catheter is a safe,method of injury,relieve symptoms quickly,Combined with gefitinib,the long-term control of malignant pleural effusion efficacy is clear. Due to the high cost of gefitinib difficult to maintain long-term application.